Cells - 37 News from the science department by Universität Bonn for the healthcare industry

Tip: You can further refine your news selection by countries.

Cells - 37 News from the science department by Universität Bonn for the healthcare industry

Tip: You can further refine your news selection by countries.

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A further step towards decoding smell

Researchers elucidate the role of individual brain neurons in human odor perception

14-Oct-2024 - We often only realize how important our sense of smell is when it is no longer there: food hardly tastes good, or we no longer react to dangers such as the smell of smoke. Researchers at the University Hospital Bonn (UKB), the University of Bonn and the University of Aachen have investigated the ...

cells nerve cells brain
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New pathway in immune defense discovered

Interaction of monocytes and platelets decoded

09-Jul-2024 - Monocytes, a special type of white blood cell, secrete cytokines as inflammatory messengers that are crucial for an appropriate immune response. Researchers at the University Hospital Bonn (UKB) and the University of Bonn have now discovered that platelets, also known as thrombocytes, communicate ...

cells monocytes blood diseases
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Breakthrough in research on brown fat

Hope for strategies that support weight loss: Researchers from Denmark and Germany have found brown fat’s “off-switch"

30-Apr-2024 - Researchers from the University of Southern Denmark, the Novo Nordisk Center for Adipocyte Signaling (SDU), the University of Bonn and the University Hospital Bonn (UKB) have found a protein that is responsible for turning off brown fat activity. This new discovery could lead to a promising ...

cells brown fat cells obesity
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New findings on the immune system: Hope for highly effective vaccines and new therapies

Underlying mechanism for the development of T follicular helper cells deciphered

05-Mar-2024 - T follicular helper cells (Tfh) are essential for strong antibody-mediated reactions of our immune system during infections and vaccinations. However, if they get out of control, this can cause diseases such as autoimmunity, allergies or cancer. Researchers from the University Hospital Bonn (UKB) ...

cells T-helper cells antibodies
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New intracellular "smoke detector" discovered

Study could lead to therapies against skin and intestinal diseases in the medium term

23-Mar-2023 - Researchers at the Universities of Bonn and Singapore have discovered a new intracellular "smoke detector." The sensor warns of damage to the mitochondria - the microscopic power plants that supply the cell with energy. If it does not function properly, chronic skin diseases can result. The ...

cells atopic dermatitis bowel diseases
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Immune cells have a backup mechanism

If the TBK1 enzyme is mutated, susceptibility to viral infections increases – unless it is missing

14-Mar-2023 - The enzyme TBK1 is an important component of the innate immune system that plays a critical role in the defense against viruses. Upon mutation-induced loss of TBK1 function, patients show an increased susceptibility to viral infections. Strikingly, if TBK1 is not expressed at all, this clinical ...

cells immune cells immune system
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Newly discovered process brings immune cells up to speed

Study identifies mechanism otherwise found in metastasizing cancer cells

18-Oct-2022 - Cancer cells use an unusual mechanism to migrate into new tissue and form metastases there. The same process probably also keeps some immune cells on their toes. This is the result of a recent study led by the University of Bonn. According to the study, certain structures, the centrioles, ...

cells centrosomes dendritic cells
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Covid-19: New energy for flagging immune cells

Hope for new treatment options

29-Jul-2022 - In severe Covid-19 patients, the metabolism produces insufficient amounts of certain energy-rich compounds called ketone bodies. However, these energy carriers are needed by two important cell types in the immune system in order to fight the virus effectively. Perhaps this finding explains why ...

cells immune cells T-helper cells
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Molecule boosts fat burning

Study identifies a new signaling molecule that increases the energy consumption of brown fat cells

07-Jul-2022 - A study led by the University of Bonn has identified a molecule - the purine inosine - that boosts fat burning in brown adipocytes. The mechanism was discovered in mice, but probably exists in humans as well: If a transporter for inosine is less active, the mice remain significantly leaner ...

cells brown fat cells fat cells
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Study shows how bioactive substance inhibits important receptor

Results from the University of Bonn raise hope for new drugs against cancer and brain diseases

29-Mar-2022 - The A2A receptor regulates how vigorously the innate immune system attacks diseased cells. Researchers at the University of Bonn have now been able to show for the first time how an important inhibitor binds to the receptor. In the future, the results will facilitate the targeted search for ...

cells immune cells cancer
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