QIAGEN and GENEART Partner to Commercialize Synthetic Human Genes
Joint development and collaboration enables enhanced production of every human protein, spurring advances in drug development
The collaboration between QIAGEN and GENEART was initiated with a joint research and development project, for which GENEART provided plasmid and gene synthesis technologies and QIAGEN supplied automated sample technologies to purify the expressed proteins. In this first of a series of ongoing collaboration projects, scientists from both companies compared optimized and normal gene sequences of 100 different proteins from the five most common protein classes, thereby generating the most comprehensive validation study of its kind. The trial showed that QIAgenes solutions achieved very high success rates of more than 90% and yielded up to 50 times more protein than conventional methods using "normal" genes by providing optimized synthetic genes and purification methods.
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