Antisoma's AS1411 granted EU Orphan Drug Status for renal and pancreatic cancer
Antisoma plc announced that its aptamer drug AS1411 has been granted Orphan Drug Status in the European Union for the treatment of renal and pancreatic cancers. This will provide a ten-year period of market exclusivity if AS1411 is approved as a treatment for either disease. The drug already has US Orphan Drug Status for both renal and pancreatic cancers.
AS1411 has shown promise in patients with renal cancer: of three who participated in a phase I trial, two showed long-term stable disease and one a near-complete response. An extension of this trial is recruiting additional renal cancer patients and will yield new data during 2006. Antisoma expects renal cancer to be an important indication for later-stage trials: the Company will seek to conduct an accelerated clinical development programme.
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