Bloome syndrome protein is critical for meiotic recombination
24-Mar-2010
- USA
Although BLM has been shown to play an important role in DNA recombination in somatic cells, there has been no information on the impact of BLM in mammalian meiosis. Now, a team led by Paula Cohen provides new data that indicate mouse BLM is involved in the proper pairing, synapsis, and segregation of homologous chromosomes during meiosis, but does not affect entry into the prophase I stage.
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