MOS-500 Spektrometer

Circular Dichroism (CD) is the most commonly employed chiroptical technique for the characterization of biomolecules and the analysis of chiral substances. The far-UV Circular Dichroism spectrum of proteins reveal important characteristics relating to their secondary structure, e.g. the percentage of alpha helix, beta-sheet or beta-turns conformation. Near-UV provides information about the direct surrounding environment of the chiral chromophores. Visible and NIR-CD spectroscopy is useful to study metal-protein interactions and to resolve individual d–d electronic transitions, and has proven to be a performant tool for enantiomeric excess determination in asymmetric synthesis. By standard, the MOS-500 offers a large range of detection techniques (absorbance, fluorescence, fluorescence anisotropy, linear dichroism, FD-CD) and can accommodate a large range of accessories to extend its standard specifications and to accept different types of liquid or solid samples. Single and multiple cell Peltier controller are available for temperature stability studies.