New drug candidates reverse drug resistance in multiple myeloma in preclinical models

31-Oct-2018 - In an article Medical University of South Carolina investigators report that a new compound enhances the efficacy of proteasome inhibitors (PIs), the standard-of-care for the treatment of multiple myeloma (MM), in cell culture and in preclinical models. The efficacy and safety of the novel ...

BioAscent receives funding for its integrated drug discovery services

28-Jun-2018 - BioAscent has secured £1.6m in funding from Maven Capital Partners (“Maven”). The investment will facilitate BioAscent’s growth through its unique offering of integrated drug discovery, and compound management services, as well as the Compound Cloud library of lead-like pharma compounds, from its ...

Eurofins opens new faciltiy in Livingston

28-Sep-2017 - Eurofins Scientific (EUFI.PA), a world leader in bioanalytical testing, has today opened a new pharmaceutical chemistry, microbiology and water microbiology facility in Livingston, Scotland, following a £4 million investment. A plaque marking the opening of the laboratories at Brucefield Industry ...

Streamlined process opens drug development to a new class of steroids

27-Sep-2017 - Researchers at Dartmouth College have developed a technique to produce synthetic steroids that could pave the way for a cascade of new drug discoveries. The process facilitates access to rare, mirror-image isomers of naturally occurring steroid structures. The technique, based on a series of new ...

Seeing more with PET scans

New chemistry for medical imaging

28-Jul-2017 - Researchers have found a surprisingly versatile workaround to create chemical compounds that could prove useful for medical imaging and drug development. The chemical mechanism, discovered by scientists at the Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab) and UC ...

Exscientia enters strategic drug discovery collaboration with GSK

Pre-clinical collaboration focused on up to 10 targets

03-Jul-2017 - Exscientia, a company for Artificial Intelligence (AI)-driven drug discovery, announces it has entered into a strategic drug discovery collaboration with GlaxoSmithKline (GSK). During this collaboration, Exscientia will apply its AI enabled platform and combine this with the expertise of GSK, in ...

Exosomes as way to make 'personalized medicine' easier and more precise

30-Jun-2017 - Today, doctors can tailor a drug therapy to your unique genetic profile, giving you the full benefits of a drug while reducing unwanted side effects -- all in harmony with the blueprints of your biology. But problems remain in the push toward "individualized medicine." For instance, genetics ...

Eurofins to invest millions in new UK facility

20-Mar-2017 - Eurofins Scientific (EUFI.PA), a world leader in bioanalytical testing, has announced plans to establish a new pharmaceutical chemistry and microbiology facility in Livingston, Scotland as part of a £4 million investment. The announcement follows Eurofins’ acquisition of Exova’s pharmaceutical, ...

New method enlists electricity for easier, cheaper, greener chemistry

22-Apr-2016 - Scientists at The Scripps Research Institute (TSRI) have found a new and better way to achieve a chemical reaction that is used widely in the pharmaceutical as well as flavor and fragrance industries. Traditional methods of "allylic oxidation" typically employ toxic and/or expensive reagents such ...

Evotec and Active Biotech Enter into Medicinal Chemistry Collaboration

09-Jun-2011 - Evotec AG announced that it has entered into a medicinal chemistry collaboration with Active Biotech AB, following the successful conclusion of a High Throughput Screening campaign to identify small molecule modulators of a priority biological target, selected by Active Biotech, involved in ...