Drugs - 7 News from the science department by Max-Planck-Gesellschaft from Germany

Drugs - 7 News from the science department by Max-Planck-Gesellschaft from Germany

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Anti-ageing drug rapamycin improves immune function through endolysosomes

Protection against an increase in pro-inflammatory factors with age

01-Mar-2024 - Rapamycin is considered a promising anti-ageing drug that improves health in old age and alleviates the age-related decline in immune function. A research group at the Max Planck Institute for Biology of Ageing has discovered in fruit flies that rapamycin activates the so-called endolysosomes, ...

drugs anti-ageing drugs autophagy
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Cell-free quest for new antibiotics

A new method combines synthetic biology with artificial intelligence

20-Nov-2023 - The rising resistance of bacteria to antibiotics presents an escalating global health risk. Now, researchers at the Max Planck Institute for Terrestrial Microbiology have combined synthetic biology and artificial intelligence (AI) to develop a more efficient approach to finding and creating new ...

drugs peptide drugs antibiotic resistance
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Do women age differently from men?

The biological sex may be a decisive factor in the effectiveness of anti-ageing drugs

06-Dec-2022 - Studies on fruit flies show how biological sex influences the effect of rapamycin, the currently most promising anti-ageing drug. Researchers from the Max Planck Institute for Biology of Ageing in Cologne and University College London report in Nature Aging that the drug only extends the lifespan ...

drugs anti-ageing drugs ageing
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Anti-ageing drug: Brief exposure to rapamycin has the same anti-ageing effects as lifelong treatment

Shorter duration of treatment may make it more likely to be used in humans

31-Aug-2022 - Brief exposure with rapamycin has the same positive effects on lifespan and health in old age as a lifelong treatment, researchers from the Max Planck Institute for Biology of Aging show in fruit flies and mice. Rapamycin is currently the most promising anti-aging drug. To maximize the medicine's ...

drugs anti-ageing drugs immunosuppressants
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Starved – New drug inhibits the growth of cancer cells

Blocking gene expression in mitochondria in mice stops cancer cells from growing

18-Dec-2020 - A newly developed compound starves cancer cells by attacking their “power plants” – the so-called mitochondria. The new compound prevents the genetic information within mitochondria from being read. Researchers from the Max Planck Institute for Biology of Ageing, the Karolinska Institute in ...

drugs cancer drugs cancer
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Tailor drugs for new targets in cancer therapy

Like a wedge in a hinge

16-Apr-2018 - In the fight against cancer, scientists are developing new drugs to hit tumor cells at so far unused weak points. Such a “sore spot” is the protein complex SF3B. Researchers led by Vlad Pena at the Max Planck Institute (MPI) for Biophysical Chemistry in Göttingen have now succeeded for the first ...

drugs cancer drugs active ingredients
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Large scale production of pharmaceuticals in tomatoes

Usage of plants as bio-factories

03-Nov-2015 - Fruits and vegetables are healthy. This is something every child knows. However, we would need to consume high amounts of many plant products to achieve an efficient dose of helpful natural compounds, because those are often low-concentrated in plants. Scientists of Dr. Alisdair Fernie’s research ...

drugs genistein natural products

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