Drugs - 5 News by MPI für Biologie des Alterns from Germany

Drugs - 5 News by MPI für Biologie des Alterns from Germany

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Anti-ageing drug rapamycin improves immune function through endolysosomes

Protection against an increase in pro-inflammatory factors with age

01-Mar-2024 - Rapamycin is considered a promising anti-ageing drug that improves health in old age and alleviates the age-related decline in immune function. A research group at the Max Planck Institute for Biology of Ageing has discovered in fruit flies that rapamycin activates the so-called endolysosomes, ...

drugs anti-ageing drugs autophagy
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Do women age differently from men?

The biological sex may be a decisive factor in the effectiveness of anti-ageing drugs

06-Dec-2022 - Studies on fruit flies show how biological sex influences the effect of rapamycin, the currently most promising anti-ageing drug. Researchers from the Max Planck Institute for Biology of Ageing in Cologne and University College London report in Nature Aging that the drug only extends the lifespan ...

drugs anti-ageing drugs ageing
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Anti-ageing drug: Brief exposure to rapamycin has the same anti-ageing effects as lifelong treatment

Shorter duration of treatment may make it more likely to be used in humans

31-Aug-2022 - Brief exposure with rapamycin has the same positive effects on lifespan and health in old age as a lifelong treatment, researchers from the Max Planck Institute for Biology of Aging show in fruit flies and mice. Rapamycin is currently the most promising anti-aging drug. To maximize the medicine's ...

drugs anti-ageing drugs immunosuppressants
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Starved – New drug inhibits the growth of cancer cells

Blocking gene expression in mitochondria in mice stops cancer cells from growing

18-Dec-2020 - A newly developed compound starves cancer cells by attacking their “power plants” – the so-called mitochondria. The new compound prevents the genetic information within mitochondria from being read. Researchers from the Max Planck Institute for Biology of Ageing, the Karolinska Institute in ...

drugs cancer drugs cancer

Fruit flies live longer with combination drug treatment

Combination drug treatment may one day be helpful at preventing age-related diseases in people

02-Oct-2019 - A triple drug combination has been used to extend the lifespan of fruit flies by 48% in a new study led by UCL and the Max Planck Institute for Biology of Ageing. The three drugs are all already in use as medical treatments: lithium as a mood stabiliser, trametinib as a cancer treatment and ...

drugs trametinib age-related diseases

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