Synthesizing fine chemicals: Technological Advance in Production of Pharmaceuticals

04-Oct-2024 - Production of fine chemicals such as those used in pharmaceuticals is typically complex and laborious. An interdisciplinary team of Fraunhofer researchers worked together across different projects to devise a method modeled on a cascade, in which multiple successive stages of synthesis proceed ...

Novel synthesis of fluorinated molecules with potential in drug research developed

The new synthetic method relies on two fundamentally challenging chemical processes

25-Jun-2024 - A research team from Kiel has described a method for directly converting carbon-hydrogen bonds in carboxylic acids into carbon-fluorine bonds. Carboxylic acids are one of the most important substance classes in chemistry and are a component of many drugs such as aspirin and ibuprofen. To tailor ...

Freeze casting - a guide to creating hierarchically structured materials

Diverse applications not only in biomedicine, but also in engineering, from new catalysts to highly porous battery electrodes

30-Apr-2024 - Freeze casting is an elegant, cost-effective manufacturing technique to produce highly porous materials with custom-designed hierarchical architectures, well-defined pore orientation, and multifunctional surface structures. Freeze-cast materials are suitable for many applications, from ...

Producing chemicals in an environmentally friendly and energy-saving way: More yield through nanopores

New membrane process increases the efficiency of enzymes - reaction rate significantly improved

22-Apr-2024 - Flow-through reactors packed with enzymes can produce certain chemicals in a gentle and careful way. However, their performance has so far been limited. A research team from the Helmholtz-Zentrum Hereon and RWTH Aachen University has now been able to increase the yield a thousandfold. Using a ...

Converting carbon dioxide into useful chemicals with the help of bacteria and solar power

How electrolysis and fermentation can be combined in one system

08-Apr-2024 - Researchers at BAM have developed a new technology that uses bacteria and solar power to produce useful chemicals from CO2. In the future, this could be used in industry to reduce greenhouse gas emissions instead of releasing them into the atmosphere. Reducing the greenhouse gas CO2 is crucial to ...

Powering Nitrogenases: New ways for sustainable fertiliser production

New targets for improving biocatalysts

26-Feb-2024 - Nitrogenases are considered promising candidates for the sustainable enzymatic production of ammonia and carbon compounds. One bottleneck in this complex process, the supply of electrons to the enzymes, has remained a mystery until now. Now a team at the Max Planck Institute for Terrestrial ...

Tobias Erb receives the Leibniz Award 2024

Innovative, interdisciplinary research approach opens up new possibilities for developing technologies to address the global climate crisis

11-Dec-2023 - Prof. Dr. Tobias Erb, Director at the Max Planck Institute for Terrestrial Microbiology and Professor at the University of Marburg, has been awarded the Gottfried Wilhelm Leibniz Prize by the German Research Foundation (DFG). The Leibniz Prize is the most important research award in Germany and ...

Releasing Brakes on Biocatalysis

The new findings could play a role in H2 technologies

01-Dec-2023 - Formaldehyde can inhibit enzymes that produce hydrogen particularly efficiently. Researchers from Bochum have discovered how this can be prevented. Enzymes from microorganisms can produce hydrogen (H2) under certain conditions, which makes them potential biocatalysts for biobased H2 technologies. ...

Primordial Photoredox Catalyst

Nitrogen-Doped Graphite Catalyzes Reactions to Give Early Biomolecules

13-Jul-2023 - The sun as a source of energy, and catalysts to accelerate chemical reactions, were of critical importance in the emergence of the first biochemical molecules on Earth. A research team has now shown that a solid deposited from ammonia and methane plasma is capable of using light energy for ...

Structure of 'oil-eating' enzyme opens door to bioengineered catalysts

Atomic level details reveal how enzyme selectively breaks hydrocarbon bonds, suggesting bioengineering strategies for making useful chemicals

04-Apr-2023 - Scientists at the U.S. Department of Energy’s Brookhaven National Laboratory have produced the first atomic-level structure of an enzyme that selectively cuts carbon-hydrogen bonds—the first and most challenging step in turning simple hydrocarbons into more useful chemicals. As described in a ...