Isotechnika Inc. granted patent for mTOR inhibitor
"Our medical device partnership with Atrium Medical makes use of TAFA93 on Atrium's drug eluting stent technology," stated Dr. Robert Foster, Isotechnika's Chairman & CEO. "This allows us to broaden our product pipeline while maintaining our primary focus in transplantation."
The Company's second drug in development is TAFA93, an advanced pro-drug of rapamycin. TAFA93 is a novel small molecule mTOR inhibitor, which is a class of drugs currently used in the prevention of organ rejection in transplantation. mTOR inhibitors are typically used in combination with calcineurin inhibitors after organ transplant. These anti-proliferative mTOR inhibitors also have utility in oncology and as drug coating for coronary stents and surgical meshes. The drug-eluting stent market was estimated at $5.5B in 2005. TAFA93 has successfully completed Phase 1 clinical trials.
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