Medivir AB enters into License and Research Collaboration Agreement on Hepatitis C

03-Dec-2004

Medivir AB has signed a license and research collaboration agreement on hepatitis C with Tibotec Pharmaceuticals Ltd, a subsidiary of Johnson & Johnson. The goal of the research collaboration is to discover and develop orally active protease inhibitors of the NS3/4A protease of HCV. Medivir has developed a novel series of potent HCV NS3/4A protease inhibitors. These HCV inhibitors exhibit antiviral properties in a cell-based assay and have drug-like properties.

Tibotec will be responsible for the global clinical development of these compounds and has acquired exclusive, worldwide marketing rights, except for in the Nordic countries, which have been retained by Medivir. The product will be commercialized in the non-Nordic countries by the Tibotec, Ortho-Biotech or Janssen Cilag operating companies of Johnson & Johnson. Under the terms of the agreement, Tibotec will make an upfront payment of EUR6.5 million and, based on successful achievement of pre-specified scientific, clinical and regulatory milestones, payments of up to EUR62 million. In addition, upon reaching a specific clinical milestone, Medivir has the right to receive a product that achieves certain predefined commercial criteria for marketing in the Nordic region or an additional payment. Medivir will receive royalties on product sales. The agreement also includes research funding.

"We are pleased to enter this collaboration and see this as evidence of Medivir's competence within protease research. Hepatitis C is the hot spot of antiviral research today. This collaboration takes Medivir another important step further on its journey towards becoming a profitable, integrated pharmaceutical company", says Medivir's CEO Lars Adlersson.

https://www.bionity.com/en/news/41289/medivir-ab-enters-into-license-and-research-collaboration-agreement-on-hepatitis-c.html