Optical scanner shows potential for real-time 3-D breast cancer screening
The device, developed primarily at Florida International University, uses a near-infrared laser diode source to produce an image of the breast tissues.
One advantage presented by the device is that it is more adaptable to breast shape and density, and that it allows imaging of the chest wall regions, which are harder to image with conventional techniques.
"The women scanned always commented on how comfortable it was to be scanned by our device - many of them said that they didn't feel anything" explains Sarah Erickson-Bhatt, an author on the paper.
The device builds an image of the tissue by mapping the optical absorption, which is altered by the concentration of haemoglobin - the protein in red blood cells. Regions with higher concentrations of haemoglobin may indicate higher blood flow due to an abnormality such as a tumour.
The optical analysis developed offers several benefits over mammography, with no ionising radiation dose and fewer issues imaging dense tissues.
"Eventually, we hope that physicians will be able to use this for real-time imaging of breast tissues as part of regular visits by the patients" adds Anu Godavarty, also an author of the paper. "We're current working on the mathematical tools required to process the images and produce 3D tomographic images, in order to determine tumour size and depth."
The researchers' on-going efforts involve extensive clinical work to demonstrate the capability of the device to pre-screen for any breast abnormality, followed by seeking FDA approvals prior to clinical use.
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Topic world Diagnostics
Diagnostics is at the heart of modern medicine and forms a crucial interface between research and patient care in the biotech and pharmaceutical industries. It not only enables early detection and monitoring of disease, but also plays a central role in individualized medicine by enabling targeted therapies based on an individual's genetic and molecular signature.
Topic world Diagnostics
Diagnostics is at the heart of modern medicine and forms a crucial interface between research and patient care in the biotech and pharmaceutical industries. It not only enables early detection and monitoring of disease, but also plays a central role in individualized medicine by enabling targeted therapies based on an individual's genetic and molecular signature.
