Aseptika Granted United States Patent for Biomarkers for Respiratory Infection Onset
The Patent granted to Aseptika in the US (Patent US8980566B2), with other worldwide applications taking place under the International Patent Treaty expected to be granted in the near future. The Patent determines the levels of activity of bacteria in the lungs of vulnerable patients with long-term conditions, such as Cystic Fibrosis (CF), Chronic Obstructive Pulmonary Disease (COPD) and Asthma.
The presence of two very different materials (biomarkers) produced by the bacterium (Pseudomonas aeruginosa) are described, in which the levels of a marker for a bacterial iron scavenging process and levels of a secreted bacterial protein are measured over time. Changes in these concentrations allow levels of bacterial activity to be determined and exacerbations of bacterial infection to be predicted and/or monitored. The methods of the invention may also be used for monitoring effectiveness of antibiotic treatment of lung infection.
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