Ascendis Pharma GmbH

Ascendis Pharma A/S is an emerging pharmaceutical company which is creating improved, patentable versions of both currently marketed drugs and high-value development-stage opportunities. The company is built upon a novel transient linker technology, TransientLink, which conjugates peptides, proteins and small molecules to a carrier molecule in a reversible fashion. This unique reversibility allows an unmodified active drug to be released (unlinked) in the body in a precise, time-controlled fashion, creating a long-acting effect. Conventional conjugation technologies are unable to achieve this type of slow-release mechanism because the polymer cannot de-link from the drug.

Ascendis’ commercial headquarters is based in Copenhagen, Denmark.Its research organization, formerly known as Complex Biosystems, is located in Heidelberg Germany.

The expertise at the two sites creates a continuum from discovery to clinical development and commercialization that will facilitate rapid product development.