Overview of specific uses of Strand Displacement Polymerases
From simple applications to complex methods
Modified polymerases have become indispensable in biotechnology and medicine. The process of PCR (polymerase chain reaction) can only be carried out with these kinds of enzymes. Introduced by K. Mullis in the 1980s and initially associated with a lot of material and time, many different, efficient PCR methods are available now. These are used across the board in research, pathogen diagnostics and genetic studies. Advantages are offered by new developments, such as strand displacement polymerases, which displace bound DNA fragments (e.g. a DNA double strand) when they come together. Shown here are application ideas and explanations of SD polymerase: from simple applications such as PCR and isothermal amplification, to more complex approaches such as WGA, to newly developed combined methods.
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Overview of specific uses of Strand Displacement Polymerases
From simple applications to complex methods