More flexibility in bioprocesses

The development pipelines of biotherapeutic products are becoming increasingly diverse. Adaptability, flexibility and agility are therefore necessary to manufacture multiple products. Bioprocess plant manufacturers must keep pace with these industry demands. This also affects components and instruments in the plants. Productivity and efficiency of bioreactors depend on effective measurement and control of process variables. This involves the use of a wide range of sensors and control devices. In many cases, a properly configured single-use bioreactor platform can be flexibly adapted to many processes. Then the process can be changed to adapt the single-use bioreactor to the new target. But the devices and sensors that control these processes must be equally adaptable. In this paper, we introduce mass flow controllers with a design and performance that makes bioprocessing equipment more flexible. We illustrate how a device's capabilities and supporting documentation increase the necessary flexibility.