RedShift BioAnalytics
Advancing Structural Characterization of Therapeutic Proteins Using MMS
Researchers at Amgen analyzed monoclonal antibodies (mAbs) using Microfluidic Modulation Spectroscopy (MMS) at concentrations ranging from 0.5 to 50 mg/mL and obtained superior data by optimizing detector dwell time settings. MMS generates reproducible data with high sensitivity at low formulation concentrations and is a more reliable and cost-effective method for evaluating secondary structure vs traditional IR techniques.
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Dr. Dipa Batabyal, Dr. Valerie Collins-Ivancic
Advancing Structural Characterization of Therapeutic Proteins Using MMS