Drug discovery and development — in space?

The low-gravity environment could speed up the development and discovery of complex molecules used in medicines

21-Nov-2022 - Carrying out scientific experiments in space allows scientists to study and make drugs without gravity, which can lead to surprising results that improve research back on Earth. According to a cover story in Chemical & Engineering News, an independent news outlet of the American Chemical Society, ...

Unexpected protein structure findings could lead to new therapies

07-Apr-2017 - Scientists have determined unexpected characteristics of a key protein linked to blood pressure control and to nerve growth, pain control and heart tissue regeneration. The findings opens doors to potential new therapies to control cardiovascular disease and pain. The protein, called AT2, is one ...

Biophysicists propose new approach for membrane protein crystallization

08-Mar-2017 - A team of scientists from the Laboratory for Advanced Studies of Membrane Proteins at MIPT, Research Center Jülich (Germany), and Institut de Biologie Structurale (France) have developed a new approach to membrane protein crystallization. For the first time, the scientists showed that membrane ...

When protein crystals grow

Chemists are investigating a substance class for biological and pharmaceutical applications

06-Jan-2017 - Annette Rompel and her team of the Department of Biophysical Chemistry at the University of Vienna are investigating so-called polyoxometalates. These compounds exhibit a great diversity and offer the scientists a wide range of applications. In interaction with enzymes they can enable the ...

Small droplets feel the vibe

10-Oct-2016 - A team of researchers at the University of Bristol have used ultrasonic forces to accurately pattern thousands of microscopic water-based droplets. Each droplet can be designed to perform a biochemical experiment, which could pave the way for highly efficient lab-on-a-chip devices with future ...

Breakthrough in mapping nicotine addiction could help researchers improve treatment

04-Oct-2016 - A scientific blueprint to end tobacco cravings may be on the way after researchers crystallized a protein that holds answers to how nicotine addiction occurs in the brain. The breakthrough at the Peter O'Donnell Jr. Brain Institute comes after decades of failed attempts to crystallize and ...

A natural light switch

Scientists have discovered and mapped a light-sensing protein that uses vitamin B12

30-Sep-2015 - The result, derived from studying proteins from the bacterium Thermus thermophilus, involves at least two findings of broad interest. First, it expands our knowledge of the biological role of vitamin B12, which was already understood to help convert fat into energy, and to be involved in brain ...

Dunn Labortechnik celebrates its 30th anniversary

01-Feb-2012 - In 1982 the company Dunn Labortechnik was founded in Asbach (Germany) by Hannelore and Peter Dunn. Since then, the company has supplied research and routine laboratories with equipment, disposables as well as immunoreagents, plasma and sera and has evolved from a nationally to an internationally ...

QIAGEN and the JCSG Announce Agreement for Commercialization of Sample Technologies for Protein Crystallography

23-Jul-2007 - QIAGEN N.V. has entered a strategic agreement with the Joint Center for Structural Genomics (JCSG), one of the 4 PSI Structural Genomics Production Centers, providing protein crystallographers with a new set of proven crystallization screens that have been assembled from analysis of hundreds of ...

Structure of Human Cytochrome P450 2D6 solved by GlaxoSmithKline with the use of Fludigm Technology

21-Mar-2006 - The TOPAZ® system for protein crystallization was instrumental in helping GlaxoSmithKline (GSK) solve the structure of cytochrome P450 2D6, an enzyme important in the metabolism of a wide variety of drugs. TOPAZ crystallization chips were used to identify positive conditions for crystallization ...