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Chromatography resins:

TOYOPEARL Super A Resin

Increase Throughput and Robustness Of Your Antibody Purification

Tosoh Bioscience GmbH

TOYOPEARL Super A resin provides a cutting-edge experience in protein A media, blending top-tier critical performance attributes with exceptional operational flexibility.

An enhanced, Animal Origin Free, recombinant Protein A ligand is bound to the polymethacrylate base bead via multipoint attachment resulting in excellent base stability for up to 100 CIP cycles with 0.5 mol/L NaOH and up to 70 CIP cycles with 1 mol/L NaOH  while  maintaining 90 % of its initial DBC.

TOYOPEARL Super A resin is available in ~45 µm particle size (F-grade) and exhibits dynamic binding capacities of greater than 70 g/L at 5 minutes residence times and greater than 60 g/L at 3 minutes residence time. Improved mass transfer characteristics allow it to maintain a larger percent of its capacity at lower residence times relative to comparable agarose based resins. It is therefore ideally suited for continuous operation using multiple short columns. This resin is also available in pre-packed SkillPak columns to simplify your process development and scale up.

Highlights

  • State-of-the-art operational flexibility: Supports high titers with high dynamic binding capacity (DBC), enhanced alkaline stability for rigorous CIP, and excellent pressure flow behavior to increase process efficiency.
  • Superior critical process performance: Features mild elution conditions, concentrated elution vol

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Chromatography resins: TOYOPEARL Super A Resin

Increase Throughput and Robustness Of Your Antibody Purification

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Topic World Chromatography

Chromatography enables us to separate, identify and thus understand complex substances. Whether in the food industry, pharmaceutical research or environmental analysis - chromatography opens up a treasure trove of information about the composition and quality of our samples. Discover the fascinating world of chromatography!

45+ products
10+ whitepaper
40+ brochures
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Topic World Chromatography

Topic World Chromatography

Chromatography enables us to separate, identify and thus understand complex substances. Whether in the food industry, pharmaceutical research or environmental analysis - chromatography opens up a treasure trove of information about the composition and quality of our samples. Discover the fascinating world of chromatography!

45+ products
10+ whitepaper
40+ brochures