Scientists identify molecular pathway that helps moving cells avoid aimless wandering

Findings from Johns Hopkins Medicine study have potential implications for understanding cancer cell spread

01-Apr-2021 - Working with fruit flies, scientists at Johns Hopkins Medicine say they have identified a new molecular pathway that helps steer moving cells in specific directions. The set of interconnected proteins and enzymes in the pathway act as steering and rudder components that drive cells toward an ...

The self-curving cornea

Cultivating 4D tissues

21-Jan-2019 - Scientists at Newcastle University have developed a biological system which lets cells form a desired shape by moulding their surrounding material - in the first instance creating a self-curving cornea. The cornea is the clear outer layer at the front of the eye ball. In the research, a flat ...

3D 'organ on a chip' could accelerate search for new disease treatments

30-Oct-2018 - Researchers have developed a three-dimensional 'organ on a chip' which enables real-time continuous monitoring of cells, and could be used to develop new treatments for disease while reducing the number of animals used in research. The device, which incorporates cells inside a 3D transistor made ...

UF scientists find first link in humans between memory and nerve cell production

26-Aug-2010 - Production of new nerve cells in the human brain is linked to learning and memory, according to a new study from the University of Florida. The research is the first to show such a link in humans. The findings, published in the journal Brain, provide clues about processes involved in age- and ...

Blocking tumor's 'death switch' paradoxically stops tumor growth

27-May-2010 - Every cell contains machinery for self-destruction, used to induce death when damaged or sick. But according to a new research study, a receptor thought to mediate cell suicide in normal cells may actually be responsible for the unrestrained growth of cancerous tumors. Blocking the activity of ...

First successful use of expanded umbilical-cord blood units to treat leukemia

20-Jan-2010 - Scientists at Fred Hutchinson Cancer Research Center have cleared a major technical hurdle to making umbilical-cord-blood transplants a more widely-used method for treating leukemia and other blood cancers. In a study published in Nature Medicine , Colleen Delaney, M.D., and colleagues describe ...

BD Biosciences and StemCell Technologies Sign License Agreements with WARF

Commercialization of Novel Culture Media and Surfaces for Human Embryonic Stem Cell Research

19-Jun-2007 - BD Biosciences, a segment of global medical technology company BD (Becton, Dickinson and Company), and StemCell Technologies, Inc. announced that they have each entered into a worldwide license agreement with the Wisconsin Alumni Research Foundation (WARF). The agreements will allow BD ...

Massachusetts Eye and Ear Infirmary to evaluate Stem Cell Innovation's PluriCells for hearing research

12-Oct-2006 - Stem Cell Innovations, Inc. announced that the Company will collaborate with Massachusetts Eye and Ear Infirmary (MEEI). Under the material transfer agreement, MEEI will evaluate PluriCells for their capacity to form the human tissues implicated in hearing loss. In return SCI will receive a ...

Stem Cell Innovations officially opened its european R&D facility in Leiden, the Netherlands

07-Jun-2006 - Stem Cell Innovations, Inc. has opened a new R&D facility to commercialise their proprietary platform of human pluripotent stem cells (PCs(TM)) in Europe. The facility is based in Leiden, the Netherlands and encompasses 1,000 m2 of state-of-the-art research laboratories. "Establishing a site in ...

Affymetrix Microarrays Uncover Genetic Mutations in Embryonic Stem Cells Approved for Federally-Funded Research

06-Sep-2005 - Affymetrix Inc. announced that a research group led by scientists at Johns Hopkins School of Medicine and the NIH used Affymetrix GeneChip(R) microarrays to discover that eight of the stem cell lines approved for federally-funded research have mutated, raising concern about the use of the ...