Roche acquires Poseida Therapeutics

Including cell therapy candidates and related platform technologies

03-Dec-2024 - Roche announced that it has entered into a definitive merger agreement to acquire Poseida Therapeutics, Inc., a public clinical-stage biopharmaceutical company pioneering donor-derived CAR-T cell therapies. Based in San Diego, California, Poseida’s R&D portfolio includes pre-clinical and ...

Side-effect free RNA therapeutics active only in diseased cells

SRTD biotech secures seed financing

18-Nov-2024 - Jülich-based biotech start-up SRTD biotech GmbH has successfully closed a seven-figure seed financing round. The company will use the fresh capital to accelerate the development of novel RNA therapeutics. Based on a proprietary platform technology, SRTD biotech aims to develop highly efficient ...

New treatment attacks brain tumors from multiple angles

Traitors turn back into defenders

13-Nov-2024 - Glioblastoma is the most common kind of malignant brain tumor in adults. So far, no treatment has been able to make this aggressive tumor permanently disappear. The tumor cells are too varied, and the microenvironment is too tumor-friendly. Researchers at the University of Basel and University ...

Diabetes switch in DNA

Promising approach for personalised diabetes therapy

07-Nov-2024 - They are underestimated genetic control elements: it is known that changes in the genome can trigger diabetes. But now researchers at the University Hospital Ulm and the INSERM Cochin Institute in Paris have shown that a previously under-researched region of the genome also plays a crucial role ...

Water-shy proteins weaken protection against cancer

Special mutations in important protective proteins lead to the proteins being broken down longer and therefore faster

31-Oct-2024 - Cancer researchers at the Faculty of Medicine at the University of Freiburg have discovered that certain "non-stop mutations" make important protective proteins against cancer in the body longer, making them "water-shy". The proteins then become more unstable in the aqueous environment of the ...

QUANTRO Therapeutics and IMP enter into research collaboration to accelerate transcriptomic drug discovery

28-Oct-2024 - QUANTRO Therapeutics (QUANTRO), a pioneer in the discovery of first-in-class transcription factor targeting cancer treatments, announced that the company is entering into a strategic research collaboration with the group of Dr. Johannes Zuber, a world-leading expert in functional genetics and one ...

A Mushroom for Colorectal Cancer Therapy

Plant fungus provides new drug with a new cellular target

22-Oct-2024 - Novel chemical compounds from a fungus could provide new perspectives for treating colorectal cancer, one of the most common and deadliest cancers worldwide. In the journal Angewandte Chemie, researchers have reported on the isolation and characterization of a previously unknown class of ...

Merck Reiterates Confidence in Returning to Sustainable Growth

Tailwind thanks to robust global growth trends in all three business sectors

18-Oct-2024 - Merck is looking confidently toward the future. At the Capital Markets Day, the company shared its expectation of profitable and financially strong growth in the coming years. After the transitional year of 2023, Merck considers the medium-term growth opportunities in its markets to be intact. ...

invIOs raises €8.2 million in a Series A to finance pipeline progress in immuno-oncology

16-Oct-2024 - invIOs GmbH, a privately held biotechnology company developing novel therapies for cancer, announced that the company has raised €8.2 million in a Series A fundraising that includes strong participation from existing shareholders and Ligand Pharmaceuticals. Ligand recently acquired APEIRON, the ...

Gene therapy against hemophilia

Hannover Medical School (MHH) is one of the first institutions in Germany to be authorized to carry out a new innovative treatment for haemophilia A and B

07-Oct-2024 - Cell and gene therapies are on the rise. This is a new glimmer of hope for people with previously untreatable or barely treatable diseases. Another new therapeutic method has now been added to the list: gene therapy for hemophilia, also known as bleeding disorder. The Hemophilia Center at ...