Therapies - 16 News by Angewandte Chemie

Tip: You can further refine your news selection by countries and industries.

Therapies - 16 News by Angewandte Chemie

Tip: You can further refine your news selection by countries and industries.

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A Mushroom for Colorectal Cancer Therapy

Plant fungus provides new drug with a new cellular target

22-Oct-2024 - Novel chemical compounds from a fungus could provide new perspectives for treating colorectal cancer, one of the most common and deadliest cancers worldwide. In the journal Angewandte Chemie, researchers have reported on the isolation and characterization of a previously unknown class of ...

therapies cancer therapy active ingredient search
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Nanocarrier with Escape Reflex

Tumor-specific drug release through controlled endosomal escape

01-Mar-2024 - Protein-based drugs must be transported into cells in a way that prevents their immediate degradation. A new approach is intended to ensure that they remain intact only in certain cells, such as cancer cells. In the journal Angewandte Chemie, a Japanese research team has introduced a nanocarrier ...

therapies protein-based therapies cancer
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Cancer Treatment with Built-in Light

Deep photodynamic therapy: photosensitizer irradiates itself

02-Sep-2021 - Therapies should be highly effective and as free as possible of side effects—a big challenge, particularly in the case of cancer. A Chinese research team has now developed a novel form of photodynamic tumor therapy for the treatment of deep tumors that works without external irradiation. The ...

therapies photo-dynamic therapies cancer
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Fighting Cancer from a Chair

Platinum complex inhibits metastasis through conformational modulation of heparan sulfate

27-Jan-2021 - Cisplatin has been used to treat cancer since the 1970s. Since then, many other platinum-containing cytostatic drugs have been developed, such as triplatinNC, a highly charged complex that contains three ligand-bridged platinum atoms. Unlike cisplatin, this drug also directly inhibits metastasis. ...

therapies cancer therapy cancer
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Combination Therapy against Cancer

Synergistic anticancer therapy with two cell killer agent systems in one nanocapsule

15-Oct-2020 - In their quest to destroy cancer cells, researchers are turning to combinational therapies more and more. Scientists from Germany and China have now combined a chemotherapeutic and photodynamic approach. All agents are encapsulated in nanocapsules with a protein shell to be delivered to the ...

therapies chemotherapy combination drug therapy
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One Drug, Three Action Modes

Chemotherapy and photodynamic therapy combined in a single drug to fight resistant cancers

17-Mar-2020 - Clinicians combat the drug resistances of some cancer types by using a combination of different drugs. To make this approach more effective, chemists have designed a chemical conjugate that can simultaneously attack several cellular targets using different modes of action. Such a single-drug ...

therapies cancer therapy combination drug therapy
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Making Puffer Fish Toxin in a Flask

Total synthesis of tetrodotoxin

10-Mar-2020 - In Japan, puffer fish is considered a delicacy, but the tickle to the taste buds comes with a tickle to the nerves: fugu contains tetrodotoxin, a strong nerve toxin. In low doses, tetrodotoxin is shown in clinical trials to be a replacement for opioids for relieving cancer related pain. In the ...

therapies cancer therapy Cross-Coupling
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Taking Aim at Gastric Cancer

New approach to selective chemotherapy

27-Jan-2020 - A novel drug, named “FerriIridium”, can simultaneously help diagnose and treat gastric cancer. The initially weakly active precursor (prodrug), based on an iridium-containing compound, is selectively activated only after reaching the interior of a tumor cell. This is possible because of the ...

therapies cancer therapy chemotherapy
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Immune System Upgrade: nanoparticles act as artificial enzymes

Catalytic immunotherapy for cancer

30-Oct-2019 - Theoretically, our immune system could detect and kill cancer cells. Unfortunately, tumors are well armed to fight these attacks. Despite modern cancer treatments, metastases and relapses remain a major problem. Increasing anti-tumor immunity might now be made possible, thanks to copper telluride ...

therapies immunotherapies cancer
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DNA Origami Full of Potent Anticancer Agents

A tailored DNA nanoplatform carries chemotherapeutic drugs and RNA interference toward multidrug-resistant tumors

23-Nov-2018 - One of the most successful techniques to combat multidrug resistance in cancer cells is the downregulation of those genes responsible for drug resistance. Chinese scientists have now developed a nanoplatform that selectively delivers small hairpin RNA transcription templates and chemotherapeutics ...

therapies cancer therapy cancer
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