Stem cells - 17 News by Max-Planck-Gesellschaft

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Stem cells - 17 News by Max-Planck-Gesellschaft

Tip: You can further refine your news selection by industries.

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A Journey back in time to the origin of stem cells

Proteins that regulate animal stem cells are much older than animals themselves

20-Nov-2024 - A new study published in Nature Communications reveals that critical proteins involved in animal stem cell regulation are much older than previously thought, predating the origin of animals that likely evolved more than 700 million years ago. The international research team included scientists ...

stem cells evolution protein-protein interaction
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More than microscopes can show

Computer simulations visualize how an essential stem cell protein opens wrapped DNA

23-Sep-2022 - A key protein for converting adult stem cells into cells that resemble embryonic stem cells has been visualized in unprecedented detail by an international team of researchers around Hans Schöler and Vlad Cojocaru of the Max Planck Institute for Molecular Biomedicine in Münster. By combing ...

stem cells computer simulations histones
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Cell-culture breakthrough: Advanced “mini brains” in the dish

Organoids that mimic human brain cortex in development and disease

27-Jun-2022 - “Outer Radial Glia” (oRG) cells are nervous system stem cells that are instrumental for the development of the human cortex and have been challenging to produce in the lab. Now, a team of Max Planck researchers from Berlin succeeded in generating brain organoids that are enriched with these stem ...

stem cells 3D cell culture 3D cell cultures
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A new dimension in Stem Cell Signaling

Molecular morse code in stem cells encrypting differentiation information revealed

01-Mar-2022 - Divide, differentiate or die? Making decisions at the right time and place is what defines a cell’s behavior and is particularly critical for stem cells of an developing organisms. Decision making relies on how information is processed by networks of signaling proteins. The teams around Christian ...

stem cells cell signaling cells
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Stem cells do not (only) play dice

Stem cells work as a team and do not leave their fate to pure chance

10-Nov-2021 - In just a few weeks a completely new organism develops from a fertilized egg cell. The real miracle is that a bunch of identical stem cells turns into completely different, specialized cell types. A team led by Christian Schröter, group leader at the Max Planck Institute of Molecular Physiology ...

stem cells embryo development embryonic development
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Fountain of youth for ageing stem cells in bone marrow

Epigenetic changes in old age increase risk of osteoporosis and bone fractures

15-Sep-2021 - As we age, our bones become thinner, we suffer fractures more often, and diseases like osteoporosis can occur. One of the culprits is ageing stem cells in the bone marrow, which are no longer as effective at replenishing the bones. Researchers from the Max Planck Institute for Biology of Ageing ...

stem cells bone marrow bones
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Embryonic development in a Petri dish

3D cell culturing technique could replace mouse embryos

14-Dec-2020 - By growing mouse stem cells in a special gel, a Berlin research team succeeded to grow structures similar to parts of an embryo. The trunk-like structures develop the precursors for neural, bone, cartilage and muscle tissues from cellular clumps within five days. This could allow the ...

stem cells 3D cell cultures embryo development
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Midbrain organoids for automated chemical screening and disease research

Max Planck Innovation licenses process for the generation of organ-like tissue aggregates to biotech company StemoniX

05-Nov-2020 - Sometimes hundreds of thousands of potential therapeutics need to be tested in large-scale, fully automated experiments to identify a single effective drug. Most compounds do not work as desired, and some are even toxic. Since the development of the induced Pluripotent Stem (iPS) Cell technology ...

stem cells induced pluripotent stem cells active ingredient research
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Neandertal genes in the petri dish

Researchers are studying the Neandertal DNA found in modern humans using stem cells and organoids

22-Jun-2020 - Protocols that allow the transformation of human induced pluripotent stem cell (iPSC) lines into organoids have changed the way scientists can study developmental processes and enable them to decipher the interplay between genes and tissue formation, particularly for organs where primary tissue ...

stem cells induced pluripotent stem cells pluripotent stem cells
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Cancer-like metabolism and human brain size evolution

Mechanism of action of human-specific brain size gene uncovered

08-Jan-2020 - The size of the human brain increased profoundly during evolution. A certain gene that is only found in humans triggers brain stem cells to form a larger pool of stem cells. As a consequence, more neurons can arise, which paves the way to a bigger brain. This brain size gene is called ARHGAP11B ...

stem cells brain stem cells brain
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