Stem cell transplantations - 56 News

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Stem cell transplantations - 56 News

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HIV cured at Charité: the next Berlin patient

Team from Charité succeeds again in apparently fully eliminating HIV from a patient’s body

22-Jul-2024 - He went down in medical history: the “Berlin Patient,” the first person in the world to be cured of HIV, following a stem cell transplant at Charité – Universitätsmedizin Berlin. Now, a team from Charité has repeated this extremely rare medical achievement. The second Berlin patient has had no ...

stem cell transplantations AIDS HI viruses
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ActiTrexx treats first patient with novel regulatory T cell therapy against Graft-versus-Host Disease

First regulatory T cell therapy from an unmatched third-party donor

26-Mar-2024 - ActiTrexx GmbH, a clinical-stage company focusing on the activation of regulatory T cells, has treated the first patient with Actileucel, its novel cell therapy for the prevention and treatment of Graft-versus-Host Disease (GvHD) in patients receiving an allogeneic haematopoietic stem cell ...

stem cell transplantations cell therapies graft versus host disease
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The gut microbiome prevents dangerous immune reactions

Certain combinations of gut bacteria protect stem cell transplantation patients

10-Jan-2024 - After stem cell transplantation, the donated immune cells sometimes attack the patients' bodies. This is known as graft versus host disease or GvHD. Researchers at the Technical University of Munich (TUM) and the Universitätsklinikum Regensburg (UKR) have shown that GvHD is much less common when ...

stem cell transplantations cancer graft versus host disease
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Cell therapy meets the very latest in gene editing: start-up Cimeio joins forces with Prime Medicine

Repairs within the body: The start-up wants to make blood stem cell transplants easier on the body

04-Jul-2023 - Gentler cell therapies for blood cancer and other serious blood diseases – this is the goal that Cimeio Therapeutics, a University of Basel spin-off, has set itself. The start-up has been able to make a great step forward together with a company that offers a pioneering method for the targeted ...

stem cell transplantations blood cancer blood stem cells
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Successful cure of HIV infection after stem cell transplantation

The "Düsseldorf patient" is the third person in the world to be completely cured of the HI virus by a stem cell transplant

21-Feb-2023 - Haematopoietic stem cell transplantation for the treatment of severe blood cancers is the only medical intervention that has cured two people living with HIV in the past. An international group of physicians and researchers from Germany, the Netherlands, France, Spain, and the United States has ...

stem cell transplantations blood cancer blood stem cells
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Endogenous molecule protects from life-threatening complications after stem-cell transplantation

Researchers find that an antimicrobial molecule modifies T-cell-signalling and thus attenuates overshooting immune reactions

19-Jan-2023 - Acute Graft-versus-host disease (GvHD) is a life-threatening complication after leukemia treatment with allogeneic stem cell transplantation, i.e. the transplantation of cells from another person. GvHD occurs when the transplanted immune cells are overly active and damage the receiving patient's ...

stem cell transplantations cancer graft versus host disease
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Immune System Reboot in MS Patients

Wiping out unwanted immune cells

14-Nov-2022 - Blood stem cell transplantation is a radical but highly effective therapy for multiple sclerosis. A study led by the University of Zurich has now examined in detail the way in which the treatment curbs the autoimmune disease and how the immune system regenerates afterwards. A better understanding ...

stem cell transplantations autoimmune diseases blood stem cells
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Making cell therapies gentler and more efficient

CHF 46 million for a University of Basel start-up

20-Apr-2022 - Cell therapies are the new hope when it comes to tackling diseases such as leukemia or multiple sclerosis, but they require an intensive and strenuous course of pretreatment. Researchers from the University of Basel and the University Hospital of Basel have developed an approach to make both this ...

stem cell transplantations autoimmune diseases blood cells
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Immune cells as squatters

Contrary to previous belief, some blood cells stay in tissues for years

01-Feb-2022 - Human immune cells not only circulate in the blood, but can also occupy certain tissues and sometimes remain there for years. A research team led by immunologist Christina Zielinski discovered this phenomenon by examining patient samples after stem cell transplantation. In addition, the ...

stem cell transplantations immune cells immune system
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Cell therapy against transplant rejection

Newly founded biotech company ActiTrexx receives funding of € 3.5 million

04-Mar-2021 - ActiTrexx GmbH, a new biotech spin-off from the University Medical Center Mainz, Germany, has successfully closed its Series A financing. A consortium led by LBBW Venture Capital GmbH with participation from MediVentures GmbH, High-Tech Gründerfonds (HTGF) and Investitions- und Strukturbank ...

stem cell transplantations cell therapies graft versus host disease
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