Single cell sequencing - 26 News

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Single cell sequencing - 26 News

Tip: You can further refine your news selection by departments, organizations, countries and industries.

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Brain-heart axis: strokes change epigenetics of immune system

Heart condition because of stroke? A new study discovers why this can happen – and how we can counter it in future

24-Jul-2024 - A stroke not only causes acute damage to the brain, but can also have long-term health implications for other organs – such as the heart. “However, there has been little research to date on the effects of brain injuries on systemic immunity,” says Professor Arthur Liesz from the Institute for ...

single cell sequencing brain epigenetics
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In severe COVID-19 cases, neutrophils work around the clock

Scientists were able to track over time what happens in molecular biology from the onset of infection to organ damage

19-Jun-2024 - The course of SARS-CoV-2 coronavirus infections depends not only on how aggressive the virus is, but also on the immune response of the infected individual. Using single-cell analyses, a group of researchers led by Samantha Praktiknjo of the Berlin Institute of Health at Charité (BIH), Markus ...

single cell sequencing coronaviruses Covid-19
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Researchers Discover Novel Cell Type that Controls the Formation and Growth of New Blood Vessels

Molecular Code Stimulates Pioneer Cells to Build Blood Vessels in the Body

19-Apr-2024 - Cardiovascular diseases, including stroke and myocardial infarction, are the world's leading causes of mortality, accounting for over 18 million deaths a year. A team of KIT researchers has now identified a new cell type in blood vessels responsible for vascular growth. This discovery may allow ...

single cell sequencing blood vessels cardiovascular diseases
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Machine learning classifier accelerates the development of cellular immunotherapies

"To finance further development, we have founded the biotech start-up Tcelltech"

19-Mar-2024 - Making a personalised T cell therapy for cancer patients currently takes at least six months; scientists at the German Cancer Research Center (DKFZ) and the University Medical Center Mannheim have shown that the laborious first step of identifying tumor-reactive T cell receptors for patients can ...

single cell sequencing artificial intelligence cancer
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Zebrafish “avatars” to help tailor glioblastoma therapies

Scientists have created a new zebrafish xenograft platform to screen for novel treatments for an aggressive brain tumor called glioblastoma

09-Oct-2023 - Glioblastoma is an aggressive and difficult-to-treat brain tumor in adults. On average, patients survive for only 1.5 years. The standard of care treatment for this disease, which includes surgery followed by radiation and chemotherapy, has not changed in 18 years. That’s partly because the ...

single cell sequencing brain tumors cancer
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Making rare cell types visible

Researchers are developing a new method

06-Apr-2023 - The human body contains more than 30 trillion cells. Until recently, the sheer number of cells in the organism meant that approaches to understanding human diseases and developmental processes based on the analysis of single cells were a futuristic vision. The development of new sequencing ...

single cell sequencing cell analysis cells
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AI analysis of cancer mutations may improve therapy

"A single test tells us something about the cellular mechanisms involved in cancer formation"

27-Jan-2023 - Combining single-cell data with a self-learning algorithm reveals how structural changes in chromosomes can trigger cancer. This new method could pave the way for personalized cancer treatments, writes a team led by Ashley Sanders in “Nature Biotechnology”. Cancer has many faces – no wonder, ...

single cell sequencing cancer chromosomes
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Pioneering method for stem cell diagnostics

Leif S. Ludwig receives Paul Ehrlich and Ludwig Darmstaedter Early Career Award

25-Jan-2023 - Biochemist and physician Dr Leif S. Ludwig (40) from the Berlin Institute of Health at Charité and the Max Delbrück Center will receive the 2023 Paul Ehrlich and Ludwig Darmstaedter Prize for Young Researchers, as the Scientific Council of the Paul Ehrlich Foundation announced. Ludwig has ...

single cell sequencing blood stem cells cell analysis
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Change with age: As bats mature their immune cells differ

Study unveils complexity of leukocytes in Egyptian fruit bat and its imprinting by age

08-Sep-2022 - A team of researchers led by Anca Dorhoi at the Friedrich-Loeffler-Institut (FLI) and Emmanuel Saliba at the Helmholtz Institute for RNA-based Infection Research (HIRI), has elucidated age-dependent variations in cellular immunity in Rousettus aegyptiacus, known as the Egyptian fruit bat, a ...

single cell sequencing B cells flow cytometry
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A potential fountain of youth for the immune system

Findings may form the basis for the development of novel therapies that help to preserve the function of the immune system in old age

30-May-2022 - In old age, the performance of the immune system decreases, and older people are more susceptible to infections. Research teams from Würzburg and Freiburg have now discovered an approach that could be used to slow down this process. The corona pandemic has made it clear: Older people are more ...

single cell sequencing CRISPR gene scissors
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