Disease genes help developing brains

Decoding – and maybe even preventing – genetic diseases

13-Sep-2021 - Holoprosencephaly (HPE) affects around one to four in every 1,000 unborns, and occurs when the cerebral hemispheres of the forebrain fail to divide or only partially divide. It is the most common malformation of the forebrain in humans and is associated with facial disfigurements, such as cleft ...

New software allows fast and straightforward analysis of environmental microbes

A user-friendly method to reconstruct and analyze SSU rRNA from raw metagenome data

10-Nov-2020 - First the background: Microbiologists traditionally determine which organisms they are dealing with using the small subunit ribosomal RNA or in short SSU rRNA gene. This marker gene allows to identify almost any living creature, be it a bacterium or an animal, and thus assign it to its place in ...

RNA structures by the thousands

New method to determine the structures of all RNA molecules in a bacterial cell at once: In the past, it would have taken many research careers

19-Jun-2020 - Every cell contains thousands of different RNA molecules. In the past, it would have taken many research careers to decipher their structures using traditional methods. But not anymore. Researchers from Bochum and Münster have developed a new method to determine the structures of all RNA ...

New Ways to Look at Protein-RNA Networks

10-Dec-2018 - For their vital tasks, all RNA molecules in our cells require proteins as binding partners. Scientists at the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) and colleagues from the European Molecular Biology Laboratory (EMBL) have developed the first method with which they ...