“Dictionaries” make fluorescence-based data for integrative structure models and their dynamics accessible

3D structures of biomolecules

ONE microscopy: from molecule to 3D structure with conventional microscopy

The simple and cost-effective method developed using a few simple but effective tricks

What triggers the programmed cell death mechanism?

Development and combination of various microscopic and spectroscopic techniques

Intricate processes in photosynthesis decoded using advanced electron microscopy technique

This enables breakthroughs in multiple areas of biological and chemical research

Research under high pressure

Why 3,000 bars are needed to take a comprehensive look at a protein

AI designs new drugs based on protein structures

“It’s a real breakthrough for drug discovery”: Process ensures right from the start that the molecules can be chemically synthesised

An enzyme makes mushrooms “magical”

New study sheds light on the structure and evolution of an enzyme in psychoactive fungi

Evolutionary history of three-finger snake toxins decoded

Hope for treatments for type 2 diabetes and hypertension

Deadly virus structures point toward new avenues for vaccine design

By comparing the structures of protein complexes from different lineages of the dangerous Lassa virus, a Scripps Research team identified new antibodies and vaccine targets

Time-resolved crystallography for the masses

“The Spitrobot will greatly accelerate research in enzymatic mechanisms"

What triggers the programmed cell death mechanism?

Development and combination of various microscopic and spectroscopic techniques

Intricate processes in photosynthesis decoded using advanced electron microscopy technique

This enables breakthroughs in multiple areas of biological and chemical research

An enzyme makes mushrooms “magical”

New study sheds light on the structure and evolution of an enzyme in psychoactive fungi

Evolutionary history of three-finger snake toxins decoded

Hope for treatments for type 2 diabetes and hypertension

Structure of wheat immune protein resolved

Important tool in the battle for food security

Most complex protein knots

Theoretical physicists put Google's artificial intelligence AlphaFold to the test and find the most complex protein knots so far

Deep learning dreams up new protein structures

Researchers show that a neural network trained exclusively to predict protein shapes can also generate new ones

Can proteins bind based only on their shapes?

A team using the nation’s fastest supercomputer to look at protein binding finds that some binding processes are simpler than expected

DeepMind and EMBL release the most complete database of predicted 3D structures of human proteins

Partners use AlphaFold, the AI system recognised last year as a solution to the protein structure prediction problem, to release more than 350,000 protein structure predictions including the entire human proteome to the scientific community

World record resolution in cryo-electron microscopy

Novel technique visualizes individual atoms in a protein with cryo-electron microscopy for the first time

Bird’s enzyme points toward novel therapies

Rice University scientists imbue cells with ‘noncanonical’ pathway to make own drugs

Deep learning dreams up new protein structures

Researchers show that a neural network trained exclusively to predict protein shapes can also generate new ones

Can proteins bind based only on their shapes?

A team using the nation’s fastest supercomputer to look at protein binding finds that some binding processes are simpler than expected

Scientists produce first open source all-atom models of full-length COVID-19 'S' protein

The protein structure facilitates viral entry into host cells making it a key target for vaccine and antiviral drug development

Showtime for photosynthesis

One of nature's most important chemical reactions is now being captured in a breakthrough 'molecular movie'

Nanodiscs catch misfolding proteins red-handed

Drug design strategy boosts the odds against resistance development

Bacterial protein structure could aid development of new antibiotics

Evolutionary link between protein structure and function discovered

Preventing protein unfolding