Mathematical modelling leads to a better understanding of prostate cancer

3D model depicts processes such as tumour growth

20-Nov-2024 - A team led by Dr Yuri Tolkach at the University of Cologne’s Faculty of Medicine and University Hospital Cologne has investigated prostate tumours and developed an advanced, realistic, three-dimensional model of prostate cancer with the help of mathematical modelling. The model depicts tumour ...

Prostate cancer: AI should help to avoid unnecessary biopsies

08-Aug-2024 - For which men is a biopsy necessary to confirm or rule out suspected prostate cancer if the PSA value is elevated? In a retrospective study, scientists from the German Cancer Research Center (DKFZ) and the Department of Urology at Heidelberg University Hospital have shown that the combination of ...

Fighting tumours down to the last cancer cell

Researchers at PSI have developed a new drug that could increase the survival chances of patients with metastatic prostate cancer

06-Jul-2023 - The drug is now being tested on patients in the PROGNOSTICS project. A research consortium consisting of the Paul Scherrer Institute, the University Hospital Basel and ETH Zurich is receiving two million Swiss francs in funding for this project. In Switzerland, about 7100 men are diagnosed with ...

Early Detection by Tango

Fast, uncomplicated, and specific: diagnosis of prostate cancer from blood samples

24-Aug-2022 - Early detection of prostate cancer, one of the most common types of cancer in men, is often achieved with PSA tests. However, this blood test for prostate-specific antigens gives many false positive results, causing unnecessary biopsies and overtreatment. In the journal Angewandte Chemie, a ...

New study associates intake of dairy milk with greater risk of prostate cancer

Authors urge men at higher-than-average risk of prostate cancer to be cautious about dairy intake

10-Jun-2022 - Men with higher intakes of dairy foods, especially milk, face a significantly higher risk of prostate cancer compared to men with lower intakes, according to a new study conducted by researchers at Loma Linda University Health. The study found no such associations between increased prostate ...

Dairy products linked to increased risk of cancer

06-May-2022 - The first major study to investigate dairy consumption and cancer risk in Chinese adults found that greater intake was associated with higher risks of liver cancer and female breast cancer. Overall evidence to date on whether eating dairy products affects the risk of cancer has been inconsistent. ...

Low-meat and meat-free diets associated with lower overall cancer risk

Risk of cancer in regular and low meat-eaters, fish-eaters, and vegetarians

25-Feb-2022 - Eating meat five times or less per week is associated with a lower overall cancer risk, according to a study published in the open access journal BMC Medicine. Cody Watling and colleagues from the University of Oxford, UK investigated the relationship between diet and cancer risk by analysing ...

Broccoli compound induces cell death in yeast

Research path for cancer treatment

26-Jan-2022 - Broccoli may contain advantages beyond nutrition. A molecule found in broccoli, cabbage and more digests down into DIM, a compound with brighter benefits than the name implies, such as inducing cell death in breast, prostate and colon cancer. Now, researchers are beginning to understand the ...

A novel approach to target enhancer-addicted cancers

A chromatin degrader stops transcription factors from driving cancer, which may serve as a potential treatment approach for over 90% of prostate cancers

03-Jan-2022 - While researchers have identified several genes that drive prostate cancer, a new study published in Nature reveals the puppet master controlling the strings. The strings: Cancer-causing genes, or oncogenes, such as androgen receptor, FOXA1, ERG and MYC. The puppet master: A chromatin remodeling ...

Predicting success in therapy with individualized cancer models

Further step in the direction of individualized medicine

11-Mar-2021 - Scientists at Urology Research Laboratory of the Department for BioMedical Research (DBMR), University of Bern and Urology Department of the Inselspital of Bern, have established organoid culture models from prostate tumor biopsies. These are small clusters of cells which can be used to test the ...