Biosynth Extends its Offering to Multi-Kilogram GMP Peptide Synthesis through the Acquisition of Pepceuticals

26-Sep-2023 - Biosynth announced the acquisition of Pepceuticals, a UK producer of synthetic peptides with multi-kilogram GMP facilities and fill-finish capabilities designed to support customers from clinical trials to commercial supply. Dr. Urs Spitz, CEO and President of Biosynth, commented, “We are very ...

mk2 Biotechnologies, WACKER and TUM jointly develop a process for the large-scale production of antimicrobial peptides based on sustainable fermentation

09-Jun-2022 - mk2 Biotechnologies, WACKER and the Technical University of Munich (TUM) announced their joint project targeting the development, large-scale production and purification of antimicrobial peptides (AMPs) for diverse applications. The project will run for two years. The aim is to take the final ...

CEM acquires key assets of Intavis Bioanalytical Instruments

31-Oct-2019 - CEM Corporation announced that it has entered into a definitive agreement to purchase the instrumentation lines of Intavis Bioanalytical Instruments AG, with headquarters in Cologne Germany. The acquisition allows CEM to strengthen its product offering in the Life Sciences for proteomics, in-situ ...

En route to custom-designed natural products

Researchers decode structure and function of docking domains in the biosynthesis of peptide natural products

23-Oct-2018 - Microorganisms often assemble natural products similar to industrial assembly lines. Certain enzymes, non-ribosomal peptide synthetases (NRPS) play a key role in this process. Biotechnologists at Goethe University have now been able to discover how these enzymes interact with each other. This ...

High efficiency synthesis of insulin by self-assembly based organic chemistry

11-May-2018 - Researchers at Tokai University, Osaka University, Tohoku University and Fukuoka University on the synthesis of insulin based on the self-assembly of polypeptide chains at about 40% efficiency. This new approach is expected to enable flexibility in synthesizing order made insulin compounds that ...

A protein that self-replicates

01-Mar-2018 - Long regarded as a biological aberration, amyloids are fibrous aggregates of short protein fragments. Amyloids have a bad reputation because they are thought to be the cause of multiple neurodegenerative diseases, including Alzheimer's, Parkinson's and Creutzfeldt-Jakob disease. It was only ...

Antibiotic insight may help in battle against bacterial resistance

21-Jul-2017 - Bacteria or 'superbugs' that have adapted to resist multiple antibiotics are responsible for around 700,000 deaths globally a year; new types of antibiotics are urgently needed. Monash University researchers, as part of an international collaboration, have identified a key part of the process by ...

A new ligand extends the half-life of peptide drugs from minutes to days

18-Jul-2017 - Peptides are biological molecules, made up of short sequences of amino acids. Because they are easy to synthesize, show low toxicity and high efficiency, peptides such as insulin and other hormones can be used as drugs. But peptides are quickly cleared by the kidneys, which means that we can only ...

New technology offers fast peptide synthesis

02-Mar-2017 - Manufacturing small proteins known as peptides is usually very time-consuming, which has slowed development of new peptide drugs for diseases such as cancer, diabetes, and bacterial infections. To help speed up the manufacturing process, MIT researchers have designed a machine that can rapidly ...

Bachem reinforced Collaboration with DOTTIKON ES

04-Oct-2016 - Bachem Group and DOTTIKON ES announce that they are extending their collaboration in the area of novel amino acids. The collaboration between the two Swiss companies covers the development, manufacturing, and distribution of enantiomerically pure amino acids, for example for peptide ...