A Deep Learning Framework For High-Quality Optoacoustic Imaging in Real-Time

Helmholtz Munich and TU Munich further develop method together with spin-off iThera Medical

11-Oct-2023 - Researchers at Helmholtz Munich and the Technical University of Munich have made significant progress in advancing high-resolution optoacoustic imaging for clinical use. Their innovative deep-learning framework, known as DeepMB, holds great promise for patients dealing with a range of illnesses, ...

Building muscle in the lab

This provides a potential for treating patients with muscle diseases – and for those who would like to eat meat, but don’t want to kill animals.

18-Aug-2023 - ETH Zurich Professor Ori Bar-​Nur and his team grow muscle cells in the laboratory. In this case, they are mouse cells, but the researchers are also interested in human and cow cells. Promising applications resonate with both: human muscle tissue cultured in the lab could be used in surgery, ...

New muscle therapy gets fast-track boost

Berlin start-up could soon be helping children with previously incurable muscle diseases thanks to an accelerated approval process

01-Aug-2023 - To help bring therapies for rare muscle diseases in children to market sooner, the Berlin-based start-up MyoPax, a spin-off from the Max Delbrück Center and Charité – Universitätsmedizin Berlin, has now received a boost from the U.S. Food and Drug Administration (FDA). The company has been ...

Smart clothing and artificial intelligence

A new technology for the diagnosis and monitoring of neurological diseases

25-Jan-2023 - International research groups led by Prof. Dr. Aldo Faisal, Professor of Digital Health at the University of Bayreuth, have developed a novel set of tools for diagnosing and monitoring neurological diseases based on body-worn sensors (wearables) and artificial intelligence. Digital biomarkers can ...

Using mRNA delivery to improve muscle strength

Targeted correction of genetic defects

16-Mar-2022 - Mutations that lead to muscle atrophy can be repaired with the gene editor CRISPR-Cas9. A team led by ECRC researcher Helena Escobar has now introduced the tool into human muscle stem cells for the first time using mRNA, thus discovering a method suitable for therapeutic applications. It may be ...

Therapy for muscular dystrophy: A new start-up

To date, there is no treatment for this life-threatening genetic disease

02-Mar-2022 - Prof. Markus Rüegg and Dr. Judith Reinhard from the Biozentrum of the University of Basel have founded the start-up SEAL Therapeutics AG together with Dr. Thomas Meier, former CEO of Santhera Pharmaceuticals. Their goal is to treat congenital muscular dystrophy using gene therapy and to bring ...

Gene scissors against incurable muscular disease

New gene correction therapy

30-Jan-2020 - Duchenne type muscular dystrophy (DMD) is the most common hereditary muscular disease among children. A Munich based team has developed a gene therapy that may provide permanent relief for those suffering from DMD. LMU researcher Eckhard Wolf was involved in the study. Muscles need dystrophin in ...

A genetic chaperone for healthy aging?

14-Aug-2019 - Researchers at the Max Delbrück Center for Molecular Medicine (MDC) have identified an epigenetic mechanism that appears to strongly influence healthy aging. It’s a protein that controls muscle integrity, lifespan and levels of an essential sugar. How does one protein have that much ...

A golden ticket to faster muscle recovery

Gold nanoparticles with cytokines reduce inflammation and promote muscle fiber regeneration

04-Oct-2018 - Anyone who has ever torn or injured a muscle knows that swelling, redness, and pain soon follow the injury: classic signs of inflammation. Inflammation is the body’s natural response to promote healing, but prolonged, excess inflammation in the muscles can contribute to the progression of chronic ...

New technique could bring earlier diagnoses for muscular dystrophy, ALS and similar disorders

07-May-2018 - A new blood test could reveal the genetic roots of muscular dystrophy, amyotrophic lateral sclerosis and other disorders caused by the expansion of DNA repeats, potentially helping doctors diagnose their patients’ conditions sooner. The findings by University of Florida Health researchers and ...