Start-up EBViously founded

Innovative vaccine based on virus-like particles

18-Dec-2024 - EBViously, a spin-off of Helmholtz Munich, officially started operations on 11 November 2024. The company is developing a preventive vaccine against diseases caused by the Epstein-Barr virus (EBV). The aim is to protect people from a range of serious diseases such as infectious mononucleosis, ...

Sanofi to acquire Principia Biopharma

Further strengthens core R&D areas of autoimmune and allergic diseases

17-Aug-2020 - Sanofi and Principia Biopharma Inc., a late-stage biopharmaceutical company focused on developing treatments for immune-mediated diseases, entered into a definitive agreement under which Sanofi will acquire all of the outstanding shares of Principia for $100 per share in cash, which represents ...

FDA Accepts File for Cladribine Tablets as Potential Treatment for Relapsing Forms of MS

01-Aug-2018 - Merck announced that a resubmission of the New Drug Application (NDA) for cladribine tablets as a potential treatment for patients with relapsing forms of multiple sclerosis (MS) has been accepted for filing by the U.S. Food and Drug Administration (FDA). “We are delighted the FDA has accepted ...

Autoimmune disorders and regulatory B cells – marker identified

30-Jan-2018 - Autoimmune disorders such as rheumatism or type 1 diabetes are on the increase world-wide. Regulatory immune cells protect healthy individuals from the disorders and combat disease progression in affected individuals. So far, little is known about the group of regulatory B cells which play a role ...

PET tracer can measure damage from multiple sclerosis in mouse models

15-Jan-2018 - The loss or damage of myelin, a cellular sheath that surrounds and insulates nerves, is the hallmark of the immune-mediated neurological disorder multiple sclerosis (MS). When segments of this protective membrane are damaged, nerve impulses can be disrupted. Symptoms range from tingling and ...

Gene therapy prevents, reverses multiple sclerosis in animal model

26-Sep-2017 - Multiple sclerosis can be inhibited or reversed using a novel gene therapy technique that stops the disease's immune response in mouse models, University of Florida Health researchers have found. By combining a brain-protein gene and an existing medication, the researchers were able to prevent ...

Experimental therapy for immune diseases hits Achilles heel of activated T cells

24-May-2017 - Immune diseases like multiple sclerosis and hemophagocytic lymphohistiocytosis unleash destructive waves of inflammation on the body, causing death or a lifetime of illness and physical impairment. With safe and effective treatments in short supply, scientists report the discovery of an ...

Molecule shown to repair damaged axons

10-Mar-2017 - A foray into plant biology led one researcher to discover that a natural molecule can repair axons, the thread-like projections that carry electrical signals between cells. Axonal damage is the major culprit underlying disability in conditions such as spinal cord injury and stroke. Andrew Kaplan, ...

MS treatment that 'resets' immune system may halt disease for at least 5 years

22-Feb-2017 - Multiple sclerosis (MS) affects around 100,000 people in the UK, and 2.3 million worldwide. The condition is caused by the immune system malfunctioning and mistakenly attacking nerves in the brain and spinal cord. This leads to a range of symptoms including fatigue, problems with arm and leg ...

An antibody-based drug for multiple sclerosis

21-Jul-2016 - Inserm Unit U919, directed by Prof. Denis Vivien ("Serine Proteases and Physiopathology of the Neurovascular Unit") has developed an antibody with potential therapeutic effects against multiple sclerosis. The study directed by Fabian Docagne paves the way for a new strategy to control the ...