Bringing Multidrug-Resistant Pathogens to their Knees

Fluorous lipopetides act as highly effective antibiotics

09-Apr-2024 - Multidrug-resistant bacterial infections that cannot be treated by any known antibiotics pose a serious global threat. In the journal Angewandte Chemie, a Chinese research team has now introduced a method for the development of novel antibiotics to fight resistant pathogens. The drugs are based ...

Photoswitchable Bactericide

Nanomaterial with “Light Switch” Kills Gram-negative or Gram-positive Bacteria

07-Dec-2023 - Healthcare-associated infections are a common problem in suppurating wound care, as is the rise in multi-drug resistant bacteria. In order to effectively and selectively combat bacterial infections, a team of researchers have developed a bactericidal nanomaterial equipped with a photochemical ...

Start-up dedicated to developing new antibiotics

Smartbax nominated for Falling Walls award

06-Nov-2023 - It all began with basic research: While conducting laboratory experiments, a team at the Technical University of Munich (TUM) came across an active agent against multidrug-resistant bacteria with a fundamental difference to antibiotics developed to date. The researchers have since established a ...

Neutrons for better vaccines against multidrug resistant germs

FRM II lets scientists look deep inside the structure of biomolecules

13-Apr-2023 - Neutrons from the Research Neutron Source Heinz Maier-Leibnitz (FRM II) can be used to explore the structure of biomolecules. The most recent success: the precise analysis of a promising vaccine against multidrug resistant germs. Bacteria which are resistant to all conventional antibiotics cause ...

New Tools Against Hospital Infections?

Encapsulated peptide blocks communication and virulence of resistant Staphylococcus

25-Apr-2022 - Antibiotic-resistant hospital pathogens are not to be underestimated as a health risk. A research team has now introduced a new approach for treating multiple-drug resistant Staphylococcus in the journal Angewandte Chemie. It is based on a synthetic peptide that reduces the virulence of the ...

From cancer medication to antibiotic

Modified cancer drug effective against multi-resistant bacteria

18-Dec-2019 - Antibiotic-resistant bacteria are increasingly the source of deadly infections. A team of scientists from the Technical University of Munich (TUM) and the Helmholtz Center for Infection Research (HZI) in Braunschweig have now modified an approved cancer drug to develop an active agent against ...

Multidrug-resistant bacteria: urban brown rats as possible source

09-Sep-2019 - Rats and the plague – that was a constant and deadly threat hanging over Europe for centuries. But the danger posed by rats to humans is not banished, albeit in a different form: a recent study shows that many rats living in Vienna are carriers of dangerous multidrug-resistant bacteria. The work ...

Novel method for rapid detection of antibiotic resistance

15-Feb-2018 - Respiratory, urinary tract, wound infections, and sepsis: the list of sites in which severe and life-threatening diseases manifest as a result of multidrug resistant microorganisms is long. The best option is an antibiotic treatment targeted specifically to the detected pathogen. However, the ...

Cluster of Resistant Tuberculosis Pathogen Discovered

10-Jan-2018 - Between February and November 2016, the Institute of Medical Microbiology at the University of Zurich discovered a multidrug-resistant Mycobacterium tuberculosis in eight refugees arriving in Europe from the Horn of Africa. The analyses provided an impulse for launching a transnational ...

A paradigm shift in multidrug resistance

24-Aug-2015 - Bacteria are pretty wily creatures. Take for example, an organism such as Salmonella, which are killed by antibiotics in lab tests, but can become highly resistant in the body. It is an example of what UC Santa Barbara biologist Michael Mahan refers to as the Trojan horse strategy. Identified ...