Physical activity and fitness – an effective approach against dementia?

05-Apr-2018 - A new therapeutic approach to improve cognitive impairment might lower the risk for dementia. By 2030, about 74 million people will be diagnosed with dementia – a number that experts have estimated because of demographic changes. Previous studies have identified that physical inactivity during ...

Heart disease, high blood pressure and diabetes may combine to worsen thinking skills

16-Nov-2016 - Research from the University of Glasgow shows that people who have a cardiometabolic disease, such as high blood pressure, diabetes or coronary heart disease (CHD), perform worse on mental tests of reasoning, memory and reaction time, and having more than one of these conditions has an even ...

Alzheimer’s study establishes way to measure resilience

14-Nov-2016 - Vanderbilt researchers have established a new measure of resilience to cognitive impairment in people with asymptomatic Alzheimer’s disease. They essentially flipped the standard approach used by researchers when mining the Alzheimer’s Disease Neuroimaging Initiative (ADNI) database, said Timothy ...

Investigating plasma levels as a biomarker for Alzheimer's disease

20-Apr-2016 - A Centre for Healthy Brain Ageing (CHeBA) paper presents the first detailed study of the relationship between plasma levels of two amyloid beta peptides (Aβ1-40 and Aβ1-42), brain volumetrics (measures studying the size of brain, which shrinks with Alzheimer's disease) and cognitive performance ...

Identifying typical patterns in the progression towards Alzheimer's disease

22-Sep-2015 - How the brain progresses from mild cognitive impairment (MCI) to Alzheimer's-type dementia has been an enigma for the scientific community. However, a recent study by the team of Dr. Sylvie Belleville, PhD, Director of the Research Centre at the Institut universitaire de gériatrie de Montréal ...

Blood protein may indicate risk of Alzheimer's disease

22-Jun-2015 - Scientists at King's College London have identified a single blood protein that may indicate the development of Mild Cognitive Impairment (MCI) years before symptoms appear, a disorder that has been associated with an increased risk of Alzheimer's disease or other dementias.The new research, ...

Simple test can help detect Alzheimer's before dementia signs show

23-Sep-2014 - York University researchers say a simple test that combines thinking and movement can help to detect heightened risk for developing Alzheimer's disease in a person, even before there are any telltale behavioural signs of dementia. Faculty of Health Professor Lauren Sergio and PhD candidate Kara ...

Novel mTOR blood tests for dementia

Unique technology seeks to identify earliest signs of Alzheimer’s disease

10-Mar-2014 - Cytox Ltd announced the start of two landmark exploratory clinical trials designed to evaluate a new blood assay platform that could potentially assist in the evaluation of an individual’s risk for dementia and Alzheimer’s. The two studies will obtain samples from patients in Europe and in the ...

Researchers discover gender-based differences in Alzheimer's disease

27-Nov-2012 - All patients with Alzheimer's disease (AD) lose brain cells, which leads to a shrinking, or atrophy, of the brain. But the pattern of gray matter loss is significantly different in men and women, according to a study presented at the annual meeting of the Radiological Society of North America ...

Biochemical signature predicts progression to Alzheimer’s disease

New potential avenues for early disease detection

16-Dec-2011 - A study led by Research Professor Matej Orešič from VTT Technical Research Centre of Finland suggests that Alzheimer’s disease is preceded by a molecular signature indicative of hypoxia and up-regulated pentose phosphate pathway. This indicator can be analysed as a simple biochemical assay from a ...