Metabolic diseases - 606 News

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Metabolic diseases - 606 News

Tip: You can further refine your news selection by departments, organizations, countries and industries.

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A New Approach for Diabetes Therapies: Inceptor Regulates Insulin Homeostasis

From Lab to Practice: A Start-up for New Diabetes Therapies

02-Dec-2024 - In 2021, a research team led by Prof. Heiko Lickert from Helmholtz Munich discovered the insulin-inhibitory receptor "Inceptor" and its role as a suppressor of the insulin signaling pathway. Now, the researchers have unlocked another, even more significant function of the receptor: it binds ...

metabolic diseases diabetes insulin
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Diabetes switch in DNA

Promising approach for personalised diabetes therapy

07-Nov-2024 - They are underestimated genetic control elements: it is known that changes in the genome can trigger diabetes. But now researchers at the University Hospital Ulm and the INSERM Cochin Institute in Paris have shown that a previously under-researched region of the genome also plays a crucial role ...

metabolic diseases diabetes CRISPR
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New Regulator of Glucose Transport in Adipose Tissue Discovered

These findings could help to develop new therapeutic approaches for treating type 2 diabetes and obesity

23-Sep-2024 - The role of the adapter protein Picalm in the development of Alzheimer's disease is well known. Now, researchers from the German Institute of Human Nutrition Potsdam-Rehbruecke (DIfE), the German Center for Diabetes Research (DZD), ETH Zurich, and the University of Cambridge have, for the first ...

metabolic diseases diabetes adipocytes
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How cells generate heat by burning calories

“People who train their brown fat through regular cold exposure are thinner and less prone to developing diabetes and cardiovascular diseases”

18-Sep-2024 - Special fat cells known as brown adipocytes help maintaining body temperature by converting calory-rich nutrients into heat. This protects from gaining excess weight and metabolic disorders. An international team of researchers led by Professor Alexander Bartelt from the Institute for ...

metabolic diseases diabetes adipocytes
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Swiss biotechnology startup HAYA Therapeutics announces collaboration with Lilly

Discovery of novel regulatory genomic targets for obesity and related metabolic conditions using proprietary RNA platform

09-Sep-2024 - HAYA Therapeutics, SA, a biotechnology company pioneering precision RNA-guided regulatory genome targeting therapeutics for chronic diseases, announced a multi-year agreement with Eli Lilly and Company to apply HAYA’s advanced RNA-guided regulatory genome platform to support preclinical drug ...

metabolic diseases lncRNA metabolic disorders
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Beige fat cells with a “Sisyphus mechanism”

A new class of fat cells makes people healthier: The cells consume energy and produce heat through seemingly pointless biochemical reactions.

16-Aug-2024 - Fat cells come in three colours: white, brown, and beige. White fat cells store fat in our body as an energy reserve. We need these cells, but having too many creates health problems. Brown fat cells are particularly active in infants. They produce heat and thus maintain the baby’s body ...

metabolic diseases diabetes beige fat cells
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A Delivery Service for Insulin

It's an old dream in pharmacy: to deliver an active ingredient to the exact place in the body where it is most needed

12-Jul-2024 - Up to three percent of people with diabetes have an allergic reaction to insulin. A team at Forschungszentrum Jülich has now studied a method that could be used to deliver the active substance into the body in a masked form - in the form of tiny nanoparticles. The insulin is only released in the ...

metabolic diseases diabetes drug delivery
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Father's Diet Before Conception Influences Children's Health

Father's body weight influences the weight of the children and their susceptibility to metabolic diseases

07-Jun-2024 - A recent study conducted by Helmholtz Munich and the German Center for Diabetes Research provides new insights into how fathers' diets and overweight can affect their children's health even before conception. The findings of the study can help develop preventive health measures for men wishing to ...

metabolic diseases diabetes adipositas
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Live long, stay healthy: Study reveals important health markers

5 tips for healthy ageing

05-Jun-2024 - In a recent study, the Leibniz Institute for Prevention Research and Epidemiology - BIPS has made significant progress in identifying health markers that are crucial for a long and healthy life. Led by Prof. Dr. Krasimira Aleksandrova and in close collaboration with the German Institute of Human ...

metabolic diseases diabetes biomarkers
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Evotec, Inserm, Lille University Hospital and Inserm Transfert enter collaboration

Identification of novel therapeutic targets in obesity and metabolic diseases

31-May-2024 - Evotec SE announced that the Company entered a partnership with Inserm, the French National Institute of Health and Medical Research, Lille University Hospital and Inserm Transfert (the private subsidiary of Inserm) to identify novel therapeutic targets and diagnostic and prognostic markers in ...

metabolic diseases adipositas metabolomics
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