15 emerging technologies that could reduce global catastrophic biological risks

11-Oct-2018 - Strategic investment in 15 promising technologies could help make the world better prepared and equipped to prevent future infectious disease outbreaks from becoming catastrophic events. This subset of emerging technologies and their potential application are the focus of a new report, ...

Reverse negative impact of ultraviolet radiation on skin

05-Aug-2015 - Over time, the sun's ultraviolet (UV) light damages the fibers in the skin called elastin. When these fibers break down, the skin begins to sag, stretch, and lose its ability to go back into place after stretching. The skin also bruises and tears more easily. The result: premature wrinkles, ...

Digoxin may be a possible treatment for prostate cancer

05-Apr-2011 - Scientists have identified digoxin as a possible therapy for prostate cancer, using a combination of laboratory science and epidemiology that is unprecedented in its cooperative nature. "Epidemiologists and basic scientists often do not understand each other, as we often are only clear on our ...

Scientists map epigenetic changes during blood cell differentiation

Potential application for stem cell therapies

17-Aug-2010 - Having charted the occurrence of a common chemical change that takes place while stem cells decide their fates and progress from precursor to progeny, a Johns Hopkins-led team of scientists has produced the first-ever epigenetic landscape map for tissue differentiation. The details of this ...

Biomarkers help predict prostate cancer progression

21-Apr-2010 - Researchers at Johns Hopkins have evaluated a simple, more specific blood test that identifies patients undergoing proactive surveillance for low-grade, low-stage, non-palpable prostate cancer who would eventually require treatment. These results, presented at the American Association for Cancer ...

Hopkins scientists discover how protein trips up germs

19-Feb-2010 - If bad bacteria lurk in your system, chances are they will bump into the immune system's protective cells whose job is gobbling germs. The catch is that these do-gooders, known as macrophages, ingest and destroy only those infectious invaders that they can securely hook and reel in. Now, Hopkins ...

Johns Hopkins researchers say vaccine appears to 'mop up' leukemia cells Gleevec leaves behind

11-Jan-2010 - Johns Hopkins Kimmel Cancer Center researchers say preliminary studies show that a vaccine made with leukemia cells may be able to reduce or eliminate the last remaining cancer cells in some chronic myeloid leukemia (CML) patients taking the drug Imatinib mesylate (Gleevec). Gleevec, one of the ...

Before or after birth, gene linked to mental health has different effects

Mouse study links timing of expression to various abnormalities

08-Jan-2010 - Scientists have long eyed mutations in a gene known as DISC1 as a possible contributor to schizophrenia and mood disorders, including depression and bipolar disorder. Now, new research led by Johns Hopkins researchers suggests that perturbing this gene during prenatal periods, postnatal periods ...

New genes implicated in high blood pressure

12-May-2009 - Researchers at the Johns Hopkins University School of Medicine, along with an international team of collaborators, have identified common genetic changes associated with blood pressure and hypertension. The study in Nature Genetics breaks new ground in understanding blood pressure regulation and ...

Quintet of proteins forms new, early-warning blood test before heart attack strikes

11-Nov-2008 - A team of Johns Hopkins biochemists has identified a mixed bag of five key proteins out of thousands secreted into blood draining from the heart's blood vessels that may together or in certain quantities form the basis of a far more accurate early warning test than currently in use of impending ...