Klaus Grohe Prize goes to Yimon Aye

50,000 euros for groundbreaking research into cell communication

28-Jun-2024 - Professor Dr. Yimon Aye, École polytechnique fédérale de Lausanne (EPFL), Switzerland, will be awarded the Klaus Grohe Prize 2024. The award, worth 50,000 euros, is one of the most highly endowed prizes for medicinal chemistry in Europe. It is awarded by the Klaus Grohe Foundation, which is part ...

Breakthrough in the production of three-dimensional molecular structures

New dimensions in organic chemistry through light-mediated synthesis

07-Apr-2021 - A major goal of organic and medicinal chemistry in recent decades has been the rapid synthesis of three-dimensional molecules for the development of new drugs. These drug candidates exhibit a variety of improved properties compared to predominantly flat molecular structures, which are reflected ...

Researchers at the forefront of developing machine learning methods for chemical discovery

Machine learning to help identify drug candidates

23-Oct-2020 - Prof. Alexandre Tkatchenko and his research team at the University of Luxembourg have been awarded grants totalling 500,000 euros to conduct research in the emerging field of machine learning methods for chemical discoveries. The discovery and formulation of new drugs, antivirals, antibiotics and ...

New drug candidates reverse drug resistance in multiple myeloma in preclinical models

31-Oct-2018 - In an article Medical University of South Carolina investigators report that a new compound enhances the efficacy of proteasome inhibitors (PIs), the standard-of-care for the treatment of multiple myeloma (MM), in cell culture and in preclinical models. The efficacy and safety of the novel ...

BioAscent receives funding for its integrated drug discovery services

28-Jun-2018 - BioAscent has secured £1.6m in funding from Maven Capital Partners (“Maven”). The investment will facilitate BioAscent’s growth through its unique offering of integrated drug discovery, and compound management services, as well as the Compound Cloud library of lead-like pharma compounds, from its ...

ChemMaps lets researchers navigate the chemical universe

06-Jun-2018 - Researchers from North Carolina State University have created a new online service - ChemMaps - that allows users to interactively navigate the chemical space of over 8,000 drugs and 47,000 environmental compounds in 3D and real time. ChemMaps is designed to be a central resource for students and ...

Selcia joins Eurofins Group

26-Jan-2018 - Selcia Limited announces that it has been acquired by Eurofins Scientific, a global leader in analytical testing and pharma discovery services. The acquisition of Selcia provides Eurofins with an entry into the custom radiolabelling and innovative pre-clinical, integrated drug discovery services ...

Common, edible mushroom has potential to kill one type of leukemia cell

09-Aug-2017 - An edible, shaggy-looking mushroom contains a protein that is a potent killer of a certain leukemia cell, a group of University of Florida researchers has found. The Coprinus comatus mushroom, commonly known as the lawyer’s wig or shaggy mane, killed human T-cell leukemia cells during laboratory ...

Seeing more with PET scans

New chemistry for medical imaging

28-Jul-2017 - Researchers have found a surprisingly versatile workaround to create chemical compounds that could prove useful for medical imaging and drug development. The chemical mechanism, discovered by scientists at the Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab) and UC ...

Exscientia enters strategic drug discovery collaboration with GSK

Pre-clinical collaboration focused on up to 10 targets

03-Jul-2017 - Exscientia, a company for Artificial Intelligence (AI)-driven drug discovery, announces it has entered into a strategic drug discovery collaboration with GlaxoSmithKline (GSK). During this collaboration, Exscientia will apply its AI enabled platform and combine this with the expertise of GSK, in ...