Fast, robust series production of nanoparticles

Next-generation encapsulation technology

08-May-2024 - Nucleic acid-based medications such as mRNA vaccines offer tremendous potential for medicine and are opening up new therapeutic approaches. These active ingredients must be enclosed inside nanoparticles to ensure that they get to where they are needed inside the body’s cells. The Fraunhofer ...

The virus hackers: RNAi therapy for viral respiratory diseases

Inhalation as a silver bullet

05-Feb-2024 - A research team from the Fraunhofer Institute for Toxicology and Experimental Medicine ITEM and the Hannover Medical School (MHH) have made significant progress in developing a new antiviral therapy. The drug, which is inhaled, uses RNAi to target and deactivate parainfluenza viruses before they ...

Better Blood Sugar Regulation

Insulin carrier triggered by glucose

19-Apr-2023 - Patients with type 1 diabetes live with a constant risk of hyper- or hypoglycemia. Precisely controlled insulin release could help to improve regulation of their blood sugar levels. In the journal Angewandte Chemie, a research team has now introduced a novel insulin formulation that can be ...

Use of Artificial Intelligence in Drug Development

WACKER, CordenPharma, LMU and HU Berlin Train Machine Learning Algorithm for the Formulation of RNA Actives

03-Apr-2023 - Together with Munich’s Ludwig Maximilian University (LMU) and the Humboldt University of Berlin (HU Berlin), Wacker Chemie AG and CordenPharma International GmbH have launched a project to accelerate the development of RNA-based drugs. The aim is to develop a new generation of lipid nanoparticles ...

Nanotechnology may improve gene therapy for blindness

New research uses lipid nanoparticles to target light-sensitive cells in the eye

18-Jan-2023 - Using nanotechnology that enabled mRNA-based COVID-19 vaccines, a new approach togene therapymay improve how physicians treat inherited forms of blindness. A collaborative team of researchers with Oregon Health & Science University and Oregon State University have developed an approach that ...

KNAUER celebrates 60th anniversary and awards science prize to a young researcher

08-Jul-2022 - The Berlin-based manufacturer of high-tech laboratory measuring instruments KNAUER Wissenschaftliche Geräte GmbH celebrated its sixtieth company anniversary with a big party on July 1, 2022 under the motto "Science with Passion". For this occasion, the company had invited about 100 guests from ...

Laboratory equipment specialist KNAUER wanted to help save the world and now received German Innovation Award

03-May-2022 - The German Innovation Award 2022 was presented in Munich on April 29. A large number of research-intensive companies had applied for the prestigious award, which is presented annually by WirtschaftsWoche. The jury, it was reported, had a hard time choosing, as only three companies from Germany ...

KNAUER celebrates 60 years of science with new technology, a science award and more

24-Feb-2022 - The Berlin-based manufacturer of high-tech laboratory instruments, KNAUER Wissenschaftliche Geräte GmbH, is celebrating its 60th anniversary this year and has some special promotions to celebrate throughout the year. 60 years – it’s not so extraordinary for a person to reach this age but for a ...

Definitive Agreement to Acquire Exelead will Strengthen Merck’s CDMO Offering for mRNA

Targeted acquisition to accelerate novel modalities service offering

07-Jan-2022 - Merck has signed a definitive agreement to acquire Exelead, a biopharmaceutical contract development and manufacturing organization (CDMO), for approximately USD780million in cash. Exelead specializes in complex injectable formulations, including Lipid Nanoparticle (LNP) based drug delivery ...

Optimization of mRNA containing nanoparticles

Investigations at FRM II aid in the development of mRNA medications

04-Jan-2022 - The research neutron source Hein Maier-Leibnitz (FRM II) at the Technical University of Munich (TUM) is playing an important role in the investigation of mRNA nanoparticles similar to the ones used in the Covid-19 vaccines from vendors BioNTech and Pfizer. Researchers at the Heinz Maier-Leibnitz ...