A new drug target for psychiatric disorders

11-Sep-2024 - Misha Kudryashev’s lab at the Max Delbrück Center has identified a molecular intermediate of a serotonin receptor that is involved in diseases such as depression and schizophrenia. The study points to a potentially new target for therapeutics. A new study published in “The EMBO Journal” points ...

Biosynth to Offer Complex Chemistry Solutions at Greater Scales Following Acquisition of VIO Chemicals

Expansion of capacity for reliable, sustainable, and flexible manufacturing solutions at any production scale.

21-Dec-2023 - Biosynth, a supplier of critical raw materials to the life science industry, announced that it has acquired VIO Chemicals, a Zurich-based company with leading chemical R&D expertise and a global network of large-scale manufacturing partners. The acquisition will expand Biosynth’s ability to ...

Biobased chemical start-up gains further strategic investors

Subsequent close of Series B financing, total raised $39 million

02-Feb-2022 - DMC Biotechnologies, Inc. announces that strategic investors Continental Grain Company, through their venture arm Conti Ventures, and Toyobo have joined the Series B fundraising round, bringing the total raised to $39 million.DMC previously announced the first close of its Series B fundraising on ...

Development of an Efficient Enantioselective Desymmetrization Strategy Using Recombinant Pig Liver Esterases

14-May-2019 - An economically significant process intensification for the efficient enzymatic synthesis of (1S,2R)-1-(methoxycarbonyl) cyclohex-4-ene-2-carboxylic acid was achieved by a careful adaption of the reaction mode to minimize mass transfer limitations. (1S,2R)-1-(methoxycarbonyl) ...

A new way to create molecules for drug development

Innovative process gives more control over free radicals

15-Oct-2018 - Chemists at The Ohio State University have developed a new and improved way to generate molecules that can enable the design of new types of synthetic drugs. Researchers say this new method of forming reactive intermediates called ketyl radicals offers scientists a way to use catalysts to convert ...

Multifunctional catalyst for poison-resistant hydrogen fuel cells

28-Jun-2017 - Japanese collaboration develops catalyst that can oxidize both hydrogen and carbon monoxide to produce energy Demand for eco-friendly fuel sources is increasing as the goal of weaning off our reliance on fossil fuels becomes commonly recognized. Hydrogen represents a possible sustainable fuel ...

Mysteries of enzyme mechanism revealed

30-Nov-2016 - An international research team led by the University of Leicester has made a breakthrough advance by trapping an intermediate in the mechanism of enzymes called heme peroxidases and determining its structure using a beam of neutrons from the heart of a nuclear reactor. The Leicester team members ...

BRAIN and Südzucker cooperate in the field of CO2 utilisation by microorganisms

15-Apr-2016 - BRAIN AG and Südzucker AG are intensifying their cooperation in the field of microbial utilisation of carbon dioxide. The cooperation, which is co-financed by the German Ministry of Education and Research (BMBF) as part of the strategic alliance ZeroCarbFP, aims at making the industrial ...

Scientists make Antarctic fish antifreeze protein in the lab

23-Jul-2013 - A team of scientists from New Zealand and the United States has chemically synthesised an antifreeze protein which helps inhibit ice crystal growth in Antarctic fish. Biological antifreezes are attractive for use in chilled foods because traditional antifreezes, such as ethylene glycol, are ...

Sensors monitor cells at work

03-Jul-2013 - Transport proteins are responsible for moving materials such as nutrients and metabolic products through a cell's outer membrane, which seals and protects all living cells, to the cell's interior. These transported molecules include sugars, which can be used to fuel growth or to respond to ...