Findings could lead to treatment of hepatitis B

07-Jun-2018 - Researchers at the University of Delaware, working with colleagues at Indiana University, have gained new insights into the virus that causes hepatitis B -- a life-threatening and incurable infection that afflicts more than 250 million people worldwide. The discovery reveals previously unknown ...

Study: Superbug MRSA infections less costly, but still deadly

17-May-2018 - Staph infections, whether MRSA (resistant to methicillin) or susceptible, are important and deadly. Drug-resistant staph infections continue to be deadlier than those that are not resistant and treatable with traditional antibiotics, but treatment costs surprisingly are the same or slightly less, ...

Molecule may help tame virulent bacteria and prevent infection

Findings discuss how Staphylococcus can colonize our noses but not cause infection

27-Apr-2018 - According to the U.S. Centers for Disease Control and Prevention, about one in three humans carries Staphylococcus aureus, or "staph," in our noses, and 2 percent of us carry the dreaded methicillin-resistant (MRSA) strain that thwarts common antibiotics. So how is it that most of us never get ...

New study identifies targets to lessen the effects of alcoholic liver disease

09-Nov-2017 - In 2015, nearly half of 80,000 deaths due to liver diseases in the United States were related to alcoholic liver disease (ALD), according to the National Institute on Alcohol Abuse and Alcoholism. Chronic alcohol consumption causes abnormal fat accumulation in liver cells (steatosis) and liver ...

Gene therapy prevents, reverses multiple sclerosis in animal model

26-Sep-2017 - Multiple sclerosis can be inhibited or reversed using a novel gene therapy technique that stops the disease's immune response in mouse models, University of Florida Health researchers have found. By combining a brain-protein gene and an existing medication, the researchers were able to prevent ...

Bristol-Myers Squibb completes previously announced acquisition of IFM Therapeutics

11-Sep-2017 - Bristol-Myers Squibb Company announced that it has completed the previously announced planned acquisition of IFM Therapeutics. The transaction includes full rights to IFM’s preclinical STING (stimulator of interferon genes)and NLRP3 agonist programs focused on enhancing the innate immune ...

Manipulating signals in bacteria could reduce illnesses

13-Jan-2017 - The University of Illinois at Chicago College of Pharmacy has received a five-year, $1.25 million federal grant to continue its research into how bacteria that cause streptococcal infections can be manipulated. By studying the chemical signals of bacteria, Michael Federle, associate professor of ...

Pfizer receives FDA approval for Prevnar 13®

Approval for adults age 18 through 49

14-Jul-2016 - Pfizer Inc. announced that Prevnar 13 ® (Pneumococcal 13-valent Conjugate Vaccine [Diphtheria CRM197 Protein]) received U.S. Food and Drug Administration (FDA) approval for an expanded age indication to include adults 18 through 49 years of age, in addition to the already approved indication for ...

Ancient anti-inflammatory drug salicylic acid has cancer-fighting properties

02-Jun-2016 - Scientists from the Gladstone Institutes have identified a new pathway by which salicylic acid--a key compound in the nonsteroidal anti-inflammatory drugs aspirin and diflunisal--stops inflammation and cancer. In a study, the researchers found that both salicylic acid and diflunisal suppress two ...

AbbVie Announces New Phase 3b Results in Genotype 1b Chronic Hepatitis C Patients with Compensated Liver Cirrhosis

26-Jun-2015 - AbbVie announced TURQUOISE-III study results demonstrating 100 percent (n=60/60) sustained virologic response at 12 weeks post-treatment (SVR12) in genotype 1b (GT1b) chronic hepatitis C virus (HCV) infected adult patients with compensated liver cirrhosis. Patients received 12 weeks of VIEKIRAX® ...