Inflammation - 48 News from the science department from Germany

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Inflammation - 48 News from the science department from Germany

Tip: You can further refine your news selection by organizations and industries.

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New potential target for colon cancer therapy

Research shows that a protein frequently found in the inflamed intestine could play an important role in the development of cancer

27-Mar-2025 - People with inflammatory bowel disease (IBD) also have an increased risk of developing colorectal cancer. However, the exact mechanisms behind this are still largely unknown. Researchers from the Cluster of Excellence “Precision Medicine in Chronic Inflammation” (PMI) and the DFG Research Unit ...

inflammation chronic intestinal inflammation gut inflammation
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Molecular 3D structure of viral "copying machine" deciphered

Approach for drug development

11-Mar-2025 - Researchers at the University Medical Center Göttingen (UMG) and the Max Planck Institute (MPI) for Multidisciplinary Sciences have shown, for the first time, how the genetic material of the Nipah virus replicates in infected cells. The virus can cause fatal encephalitis in humans. Using ...

inflammation brain inflammations cryo-electron microscopy
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Immune cells with a dual role: switching between protection and attack

Rsearchers show that a certain type of immune cell acts more flexibly than previously thought - with potential for new therapeutic approaches

03-Mar-2025 - As part of the innate immune system, dendritic cells are part of the body's first line of defense against infections. They recognize pathogens and coordinate the immune response. An international team led by Professor Barbara Schraml from LMU's Biomedical Center has now comprehensively ...

inflammation allergies autoimmune diseases
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Hepatitis D: When the immune system gets out of control

Researchers have identified a marker on natural killer cells that is influenced by the anti-inflammatory effectiveness of the drug bulevirtide

10-Feb-2025 - Hepatitis D viruses (HDV) cause the most severe form of chronic, virus-related hepatitis. The active ingredient bulevirtide has been on the European market since mid-2023 as the only approved treatment option to date. The drug attaches to the binding site that blocks the docking point for the ...

inflammation liver inflammation hepatitis B
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SARS-CoV-2 Spike Protein Accumulation Linked to Long-Lasting Brain Effects

Researchers have identified a mechanism that may explain the neurological symptoms of Long COVID

03-Dec-2024 - The study shows that the SARS-CoV-2 spike protein remains in the brain’s protective layers, the meninges, and the skull’s bone marrow for up to four years after infection. This persistent presence of the spike protein could trigger chronic inflammation in affected individuals and increase the ...

inflammation brain inflammations brain
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Cellular “power plants” control inflammation

Researchers discover how mitochondria not only produce energy but also influence inflammation

28-Nov-2024 - Whether cells in the human body survive or die under stress depends, among other things, on their mitochondria. Scientists at the Faculty of Medicine at the University of Freiburg have now shown that a sudden stop in energy production in these cell “power plants” prevents normal cell death or ...

inflammation cell death cells
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Rapid success: innovative therapy stops deadly brain inflammation

’We are convinced that our method will revolutionise the treatment of infectious diseases’

27-Nov-2024 - Progressive multifocal leukoencephalopathy (PML) is a rare but serious brain infection. It gradually destroys brain tissue and often leads to death within a few weeks. It is caused by the human polyomavirus 2 – also known as the John Cunningham (JC) virus. In 2021, an interdisciplinary team at ...

inflammation brain inflammations brain
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Central mechanism of inflammation decoded

Researchers use nanobodies to elucidate pore formation by gasdermin D in cell membranes

01-Oct-2024 - The formation of pores by a particular protein, gasdermin D, plays a key role in inflammatory reactions. During its activation, an inhibitory part is split off. More than 30 of the remaining protein fragments then combine to form large pores in the cell membrane, which allow the release of ...

inflammation cell death cell membranes
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Trigger points for bowel cancer found at a young age

Regenerative stem cells as the origin of inflammation-associated intestinal tumors

03-Jul-2024 - If you ask a cell biologist how cancer develops, the answer is: through a mutation in a stem cell. In a new publication in the journal "Nature Genetics", scientists from the Erasmus Medical Center (Erasmus MC) in Rotterdam and the Philipps University of Marburg break this dogma. They show that an ...

inflammation chronic inflammation chronic intestinal inflammation
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In severe COVID-19 cases, neutrophils work around the clock

Scientists were able to track over time what happens in molecular biology from the onset of infection to organ damage

19-Jun-2024 - The course of SARS-CoV-2 coronavirus infections depends not only on how aggressive the virus is, but also on the immune response of the infected individual. Using single-cell analyses, a group of researchers led by Samantha Praktiknjo of the Berlin Institute of Health at Charité (BIH), Markus ...

inflammation lung inflammation coronaviruses
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