Immunotherapies - 26 News from the science department from Germany for the healthcare industry

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Immunotherapies - 26 News from the science department from Germany for the healthcare industry

Tip: You can further refine your news selection by organizations.

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Leveraging intercellular mitochondria transfer to boost cancer immunotherapies

A new cancer busting platform

17-Sep-2024 - An international team of researchers, led by Professor Luca Gattinoni at the Leibniz Institute for Immunotherapy (LIT), has developed an innovative mitochondrial transfer platform to supercharge CD8+ T cells, enabling them to overcome exhaustion and more effectively fight tumor cells. Cancer ...

immunotherapies cancer immunotherapies cancer
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"Sleep timer" for immune cells discovered

Hepatitis B: Liver cells switch off the immune response

15-Jul-2024 - In chronic hepatitis B, the liver contains immune cells that could destroy hepatitis B virus-infected cells but are inactive. A team from the Technical University of Munich (TUM) has discovered that cells in blood vessels in the liver start a “sleep timer” that switches off immune cells. ...

immunotherapies chronic hepatitis B endothelial cells
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Tumor cells evade the immune system early on

Newly discovered mechanism could significantly improve cancer immunotherapies

26-Apr-2024 - Tumors actively prevent the formation of immune responses by so-called cytotoxic T cells, which are essential in combating cancer. Researchers at the Technical University of Munich (TUM) and the Ludwig-Maximilians-Universität München (LMU) Hospital have now uncovered for the first time how this ...

immunotherapies cancer immunotherapies cancer
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Machine learning classifier accelerates the development of cellular immunotherapies

"To finance further development, we have founded the biotech start-up Tcelltech"

19-Mar-2024 - Making a personalised T cell therapy for cancer patients currently takes at least six months; scientists at the German Cancer Research Center (DKFZ) and the University Medical Center Mannheim have shown that the laborious first step of identifying tumor-reactive T cell receptors for patients can ...

immunotherapies artificial intelligence cancer
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Computer-engineered DNA to study cell identities

“We can follow with our eyes the color in a petri dish when we give a treatment”

12-Feb-2024 - A new computer program allows scientists to design synthetic DNA segments that indicate, in real time, the state of cells. Reported by the Gargiulo lab in “Nature Communications”, it will be used to screen for anti-cancer or viral infections drugs, or to improve gene and cell-based ...

immunotherapies artificial DNA cancer
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Innovative research aims to improve wound healing and cancer therapy

Freiburg researcher Priscilla Briquez receives ERC Starting Grant for innovative approach to protein engineering

30-Oct-2023 - Jun.-Prof. Dr. Priscilla Briquez, junior professor at the Department of General and Visceral Surgery at the Freiburg University Medical Center and member of the Medical Faculty at the University of Freiburg, has received a European Research Council (ERC) Starting Grant from the European ...

immunotherapies cancer immunotherapies ERC Starting Grant
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Transgenic T cells against malignant brain tumors

New form of therapy tested

29-Sep-2023 - Scientists from the German Cancer Research Center (DKFZ) and the University Medical Center Mannheim (UMM) successfully tested a new form of cellular immunotherapy against brain tumors in mice for the first time. Glioblastomas are the most aggressive of all brain tumors. They spread diffusely in ...

immunotherapies adoptive T cell therapy brain
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A protein on cancer cells supports immune response against tumors

Surprising discovery

19-Sep-2023 - Scientists from the German Cancer Research Center (DKFZ) identify a new and surprising function of a membrane protein on the surface of cancer cells: It supports and stabilizes an important "co-stimulatory" factor that enhances the activation of T cells, thus improving the immune response against ...

immunotherapies cancer immunotherapies cancer
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High honor for pioneers of cancer immunotherapy

Meyenburg Prize goes to Katalin Karikó, Uǧur Șahin and Özlem Türeci

23-Mar-2023 - The Meyenburg Prize 2020/21, endowed with 100,000 €, goes to Katalin Karikó (University of Szeged and Pennsylvania), Özlem Türeci and Uǧur Șahin (BioNTech AG and Universitätsmedizin Mainz). The researchers receive the award for their outstanding contributions to the development of vaccines and ...

immunotherapies cancer immunotherapies cancer
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New Players in the Immune Response

This discovery has consequences – for vaccination strategies as well as for immunotherapies against cancer

25-Aug-2022 - Lymph nodes trigger very different immune responses – depending on which body tissue they are connected to. Special T cells are responsible for this newly discovered relation. The human body contains 600 to 800 lymph nodes, which are specialised organs that trigger immune responses. To be ...

immunotherapies cancer immunotherapies cancer
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