Epigenetics and neural cell death

28-Oct-2016 - LMU researchers have demonstrated how deregulation of an epigenetic mechanism that is active only in the early phases of neurogenesis triggers the subsequent death of neural cells. The generation of neurons from stem and progenitor cells is a complex, tightly regulated process known as ...

When cells run out of fuel

Parkinson's genes ensure the energy supply of neurons

26-Aug-2009 - Parkinson's disease is caused by the degeneration of neurons in the midbrain. The mechanisms leading to the loss of these neurons, however, are largely unknown. Recent research revealed that about ten per cent of cases are caused by defects in so-called Parkinson-associated genes. Furthermore, ...