Fluorescence - 13 News from the science department by Angewandte Chemie

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Fluorescence - 13 News from the science department by Angewandte Chemie

Tip: You can further refine your news selection by countries and industries.

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Tracking Depression

Molecular probe specifically detects serotonin in fluorescence imaging

10-Sep-2024 - Serotonin in depression is highly relevant in diagnosis, treatment, and drug development. To better study this area, a Chinese team has now developed a fluorescent probe for imaging processes that is highly sensitive and selective toward serotonin. In the journal Angewandte Chemie, they also ...

fluorescence depressions imaging
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Continuous Glucose Monitoring

Tissue-Integrated Sensitive Glucose Nanosenor Using Inactive Glucose Oxidase Enzyme

09-Jan-2024 - Monitoring glucose levels is one of the key elements in health monitoring. A research team has now developed a battery-independent fluorescent nanosensor based on single-wall carbon nanotubes and an inactive form of the enzyme glucose oxidase (GOx). Because the enzyme is not in its active form, ...

fluorescence blood sugar carbon nanotubes
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Tracking down Environmental Toxins

Detection of per- and polyfluoroalkyl substances (PFAS) by interrupted energy transfer

02-Nov-2023 - PFAS, a family of highly fluorinated substances, represent a danger for humans and the environment. Particularly problematic members of this family, such as perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA) appear to cause organ damage and cancer, as well as disrupting the ...

fluorescence fluorescence measurements fluorescence sensors
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A molecular shield for near-infrared fluorescent dyes

Stable and Functional Dyes for Near-Infrared Fluorescence Imaging of Living Subjects

05-Jun-2020 - Scientists can monitor biomolecular processes in live tissue by noninvasive optical methods, such as fluorescence imaging. However, the fluorescent dyes used for that purpose are often rather unstable, and photobleaching, lack of specificity, and poor pharmacokinetics are recurrent issues. US ...

fluorescence chromophores fluorescence imaging
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Staining Cycles with Black Holes

Ultrafast repeated staining and destaining of cell samples for tumor diagnostics

27-Mar-2020 - In the treatment of tumors, microenvironment plays an important role. It often contains immune cells that are so changed that they promote tumor growth. In the journal Angewandte Chemie, scientists have introduced a method by which cell samples from tumors and their surroundings can rapidly ...

fluorescence click chemistry fluorescent quencher
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Microglia Turned On

Visualizing microglia in brain tissue with a fluorescence turn-on substrate

20-May-2019 - Part of the immune system in the brain is made up of so-called microglia cells. Korean and Singaporean researchers have now developed a fluorescent probe that specifically labels this type of macrophage. The cells were visualized in cell culture and in the live brains of rodents. As detailed in ...

fluorescence brain fluorescence imaging
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Tracking Small Things in Cells

Small and tunable fluorophores for the imaging of metabolites in living cells

02-May-2019 - Living cells can react to disturbances with a changed metabolism, but direct observation of trafficking metabolites in live cells is difficult. An international team of scientists has now developed a class of remarkably small fluorophores called SCOTfluors. The dyes emit light in the visible to ...

fluorescence cell metabolism cells
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Water-Soluble Warped Nanographene

Synthesis of a water-soluble warped nanographene and its application for photo-induced cell death

13-Feb-2018 - Graphene and its nano-sized little sibling, nanographene, are well known for their remarkable photoelectronic properties. However, biomedical applications are hampered by the insolubility of the materials, especially in water. A Japanese team of scientists has now introduced substituted “warped ...

fluorescence borylation cancer therapy
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Acoustic Nanomotors

Active delivery of Cas9-sgRNA complex in the cell by using ultrasound-propelled nanomotors

13-Feb-2018 - In cancer research, the “Cas-9–sgRNA” complex is an effective genomic editing tool, but its delivery across the cell membrane to the target (tumor) genome has not yet been satisfactorily solved. American and Danish scientists have now developed an active nanomotor for the efficient transport, ...

fluorescence cancer therapy CRISPR

4-in-1

Targeted gene suppression in cancer cells

12-May-2009 - Diagnosis and treatment in one go: Korean researchers led by Tae Gwan Park and Jinwoo Cheon have developed the basis for a four-in-one agent that can detect, target, and disable tumor cells while also making them macroscopically and microscopically visible. As they report in the journal ...

fluorescence contrast agents endocytosis
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