New perspectives for personalized therapy of brain tumors

Stem cell expert recently founded a spin-off to further explore the potential of IPTOs for drug testing

13-Feb-2025 - Scientists from the German Cancer Research Center (DKFZ) and ShanghaiTech University have developed an innovative method for growing brain tumors of individual patients in the laboratory that mimic the original structure and the molecular property of the parental tumor as closely as possible. ...

Multiple myeloma: When cancer cells break out of the bone marrow, a dangerous diversity arises

The findings could be crucial for the further development of diagnostics and therapy

12-Feb-2025 - A research team from the Heidelberg Medical Faculty, the German Cancer Research Center (DKFZ), the Berlin Institute of Health at Charité (BIH) and the Max Delbrück Center has discovered new details about the spread of the incurable bone marrow cancer multiple myeloma in the body: When the cancer ...

Low-cost cancer prevention: AI-generated influencers reach at-risk groups on social media

The researchers see great potential in AI-driven influencers for future public health campaigns

29-Jan-2025 - Artificial Intelligence (AI) is transforming cancer prevention: A groundbreaking study conducted at the German Cancer Research Center (DKFZ) demonstrates that AI-generated social media influencers can effectively reach at-risk groups with preventive health messages—at a fraction of the cost of ...

New approach to fighting cancer: energy trap for tumor cells

Findings could pave the way for new, highly specific therapies that target the weaknesses of cancer metabolism while sparing healthy cells

22-Jan-2025 - Glycolysis is an important sugar degradation pathway that cancer cells in particular depend on. Scientists at the German Cancer Research Center (DKFZ) have now shown that liver cancer cells in mice and humans depend on a key enzyme of glycolysis, Aldolase A. When it is switched off, glycolysis ...

Breakthrough: Mini-tumors cultivated from circulating cancer cells for the first time

New approaches against metastatic breast cancer

07-Jan-2025 - Tumor cells circulating in the blood are the "germ cells" of breast cancer metastases. They are very rare and could not be propagated in the culture dish until now, which made research into therapy resistance difficult. A team from the German Cancer Research Center (DKFZ), the Heidelberg Stem ...

Joint research on the next generation of sun screens

The German Cancer Research Center (DKFZ) and Beiersdorf are cooperating on the development of innovative sun protection products

16-Dec-2024 - Experts predict that climate change and the associated increase in the number of hours of sunshine will lead to a further increase in skin cancer cases. This is particularly to be expected for non-melanoma skin cancer, which is diagnosed around 210,000 times in Germany every year. This term ...

“And the Science Awards go to…”

Bayer Foundation announces Science Awards winners of 2024

08-Nov-2024 - Professor Meritxell Huch receives this year’s Otto Bayer Award. The Otto Bayer Award is presented alternating with the Hansen Family Award every second year. The award recognizes leading scientists working in German-speaking countries for ground-breaking research in chemistry or biochemistry. The ...

Epigenetic changes reprogram astrocytes into brain stem cells

Discovery shows that astrocytes could potentially be used in regenerative medicine to replace damaged nerve cells

09-Sep-2024 - Resting brain stem cells hardly differ from normal astrocytes, which support the nerve cells in the brain. How can almost identical cells perform such different functions? The key lies in the methylation of their genetic material, which gives these special astrocytes stem cell properties. ...

Prostate cancer: AI should help to avoid unnecessary biopsies

08-Aug-2024 - For which men is a biopsy necessary to confirm or rule out suspected prostate cancer if the PSA value is elevated? In a retrospective study, scientists from the German Cancer Research Center (DKFZ) and the Department of Urology at Heidelberg University Hospital have shown that the combination of ...

Phagocytes from the culture dish for cancer therapy

"Our induced phagocytes have the potential to destroy cancer cells in therapeutic applications by devouring them"

13-Jun-2024 - Cell-based cancer therapies often fail nowadaystoday because the immune cells are unable to penetrate the tumor efficiently. The use of certain phagocytes is considered a promising alternative - but until now it has not been possible to grow them in sufficient quantities in the culture dish. ...