Scientists from 33 European countries join forces to generate reference genomes for the continent's rich biological diversity

19-Sep-2024 - The European Reference Genome Atlas (ERGA) pilot project reports its success in uniting scientists from across Europe to produce high-quality reference genomes for 98 species. This marks a significant milestone in the quest to create a high-quality reference genome database for all European ...

A breakthrough in understanding COVID-19 proteins

Researchers have released a revolutionary database for molecular dynamics simulations

15-Jan-2024 - Designed to meet the urgent need for insights into the molecular intricacies of SARS-CoV-2 infection, BioExcel-CV19 is a repository for Molecular Dynamics (MD) simulations. Researchers at IRB Barcelona, led by Dr. Modesto Orozco, have built this database including key flexibility information ...

Making the most of minuscule metal mandalas

This achievement has the potential to drive new discoveries and advancements in fields like catalysis, medicine, and beyond

23-Jun-2023 - To unveil the previously elusive behavior and stability of complex metal compounds found in aqueous solutions called 'POMs', researchers at the University of Vienna have created a speciation atlas now published in Science Advances. This achievement has the potential to drive new discoveries and ...

Self-teaching AI uses pathology images to find similar cases, diagnose rare diseases

New model acts as search engine for large databases of pathology images

14-Oct-2022 - Rare diseases are often difficult to diagnose and predicting the best course of treatment can be challenging for clinicians. Investigators from the Mahmood Lab at Brigham and Women’s Hospital, a founding member of the Mass General Brigham healthcare system, have developed a deep learning ...

Unchartered territory in the human genome

18-Jul-2022 - An international consortium brings together 7,200 segments of the human genome that are virtually unexplored and presents a roadmap for integrating them into genome databases in “Nature Biotechnology”. They could hold information about what sets humans apart from other animals. When researchers ...

New genes with mutations for developmental disorders identified

Tracking down the causes of rare diseases in children

29-Jun-2022 - The causes of intelligence impairment or epilepsy remain unexplained in more than 50 per cent of cases. Together with international colleagues, researchers at Leipzig University Hospital have discovered two genes with mutations that cause neurodevelopmental disorders in children. Their findings ...

Tapping the ocean as a source of natural products

New species and new molecules discovered

24-Jun-2022 - Using DNA data, ETH researchers have examined seawater to find not only new species of bacteria, but also previously unknown natural products that may one day prove beneficial. The oceans are teeming with countless forms of life, from the world’s largest creature – the blue whale– to miniscule ...

Green wave for “gene cabs”

Leap in knowledge of peptide nanofibrils

03-Jun-2022 - Viruses help researchers to introduce genes into cells so that they can produce active pharmaceutical ingredients, for example. Special peptides stimulate the process. Until now, however, the efficiency increase was poorly understood. A team of researchers from the MPI for Polymer Research, the ...

New Drug Candidates from Known Compounds

Big data platform for drug repurposing presented

03-Dec-2021 - The need for new drugs is high. Researchers at Technische Universität Braunschweig , together with colleagues from other universities, have presented a new platform for drug repurposing. This platform facilitates the search for new therapeutics. The results were published in the journal Nature ...

Fighting blood diseases with artificial intelligence

Largest open-source database for bone marrow cell images developed

24-Nov-2021 - How can we better diagnose blood diseases? A research group led by Helmholtz Munich aims to answer this question with artificial intelligence (AI). Their goal is to facilitate the time-consuming analysis of bone marrow cells under the microscope. The researchers developed the largest open-source ...