Cryo-electron microscopy - 3 News from the science department by MPI für molekulare Physiologie from Germany

Cryo-electron microscopy - 3 News from the science department by MPI für molekulare Physiologie from Germany

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Identify, engage, assassinate: How seahorse-like toxins kill insects

Researchers reveal the first-ever detailed structure of the bacterial toxin Mcf1: Useful for engineering novel biopesticides

02-Feb-2024 - Insect-killing bacteria typically release toxins to slay their hosts. The bacterium Photorhabdus luminescens, for example, pumps insect larvae full of the lethal ‘Makes caterpillars floppy 1’ (Mcf1) toxin, leading them to first become droopy and then dead. However, it has so far been a mystery ...

cryo-electron microscopy bacterial toxins biopesticides
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Structure of key protein for cell division puzzles researchers

Researchers provide a first 3D snapshot of the CCAN protein complex and raise fundamental questions towards the creation of artificial chromosomes

17-May-2022 - Human cell division involves hundreds of proteins at its core. Knowing the 3D structure of these proteins is pivotal to understand how our genetic material is duplicated and passed through generations. The groups of Andrea Musacchio and Stefan Raunser at the Max Planck Institute of Molecular ...

cryo-electron microscopy cell division centromeres
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Ordered from afar: How germs’ toxins become dangerous

Researchers highlight the mechanism that enhances toxicity of pathogens in the human cell

19-Nov-2021 - The bacterium P. aeruginosa causes the most common secondary infection in hospital patients with influenza, COVID-19 or cystic fibrosis and it is resistant to antibiotics. Another bacterial pathogen, Vibrio vulnificus, is found in raw seafood and brackish waters and can have rare, but deadly ...

cryo-electron microscopy Pseudomonas aeruginosa toxins

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