Could eating turkey ease colitis?

According to data in mice, extra tryptophan could reduce the risk of future colitis flares

28-Nov-2023 - Thanksgiving is often a time for thinking about your belly. For those with an inflammatory bowel diseases like ulcerative colitis, feasting can be associated with stress, even when food isn’t a trigger for the painful symptoms. New research in mice suggests that certain foods – especially those ...

How sugar promotes inflammation

Excessive sugar consumption can promote inflammatory processes in the body and facilitate the development of autoimmune diseases.

24-Mar-2022 - People who consume sugar and other carbohydrates in excess over a long period of time have an increased risk of developing an autoimmune disease. In affected patients, the immune system attacks the body's own tissue and the consequences are, for example, chronic inflammatory bowel diseases such ...

Immune responses in chronic inflammatory bowel diseases

New population of immune cells that is highly abundant in Crohn’s disease patients

17-Mar-2022 - Chronic inflammatory bowel diseases (IBDs) like Crohn's disease and ulcerative colitis are characterized by inflammation of the gastrointestinal tract which flares up in phases and which is accompanied by abdominal pain, diarrhea and severe impairment of the quality of life. The inflammation is ...

Researchers identify pathway critical for the development and prevention of intestinal inflammation

Potential for novel therapeutics

10-Nov-2021 - Inflammatory bowel diseases (IBD), including Crohn's disease and ulcerative colitis, are chronic inflammatory diseases of unknown origin. While genetics was shown to contribute to IBD risk, only a minority of people carrying genetic risk variants develop the disease. It suggests that other ...

Breakthrough in the development of new anti-inflammatory therapies

Novel approach to treatment also works in patients with inflammatory bowel diseases

09-Mar-2021 - Chronic inflammatory bowel diseases (IBD), such as Crohn's disease and ulcerative colitis, lead to repeated flares of chronic diarrhea, fever and pain, as well as severe psychological stress. In Germany, around 320,000 people are affected by IBD. A disturbed immune response leads to inflammation ...

Cells that destroy the intestine

Medical researchers discover a type of cell which induces acute inflammatory episodes in bowel diseases

31-Jan-2019 - More than 4000,000 people in Germany are affected by the chronic inflammatory bowel diseases Morbus Crohn or ulcerative colitis. Patients often suffer from flare-ups, which damage intestinal tissue. Until now, little has been known about what actually causes flare-ups. Working together with ...

Why asbestos is so dangerous

09-Mar-2018 - Long, pointed asbestos fibres induce chronic inflammation, which can lead to cancer. SNSF-funded researchers have found underlying mechanisms for this and hope their results will help prevent damage. The fact that asbestos causes cancer has been largely undisputed for nearly 50 years. Now, ...

Immune cells that keep gut fungi under control

15-Jan-2018 - Immune cells that process food and bacterial antigens in the intestines control the intestinal population of fungi, according to a new study from Weill Cornell Medicine scientists. Defects in the fungus-fighting abilities of these cells may contribute to some cases of Crohn's disease and other ...

Potent parasite protein - New therapeutic options for inflammatory bowel conditions?

24-Nov-2017 - A single protein from a worm parasite may one day offer new therapeutic options for treating inflammatory bowel diseases like Crohn’s or Ulcerative Colitis, that avoid the potentially serious side effects of current immunosuppressant medications. The study demonstrates the discovery of a distinct ...

Titanium dioxide nanoparticles can exacerbate colitis

20-Jul-2017 - Titanium dioxide, one of the most-produced nanoparticles worldwide, is being used increasingly in foodstuffs. When intestinal cells absorb titanium dioxide particles, this leads to increased inflammation and damage to the intestinal mucosa in mice with colitis. Researchers at the University of ...