Modifiable risk factors responsible for half of cardiovascular diseases

Regional differences in risk factors

29-Aug-2023 - Scientists of the Global Cardiovascular Risk Consortium under the auspices of the Department of Cardiology at the University Heart & Vascular Center of the Medical Center Hamburg-Eppendorf (UKE) and the German Center for Cardiovascular Research (DZHK) have proven that the five classic ...

Repelling disorder: What makes cholesterol-containing surfaces so repulsive?

The development of synthetic materials using the discovered principle is promising

26-Jun-2023 - Living organisms use powerful physical principles to control interactions at their surfaces. Researchers at the Leibniz Institute of Polymer Research Dresden, Leipzig University and TU Dresden have now discovered why cholesterol-containing surfaces can exhibit greatly reduced attachment of ...

High Cholesterol, Overweight and Reduced Physical Stamina Are Long Covid Sequelae in Young Adults

06-Sep-2022 - Healthy young people with just a mild Covid infection can sometimes suffer temporary post-infection consequences such as tiredness, loss of smell and taste or reduced fertility. These symptoms usually improve with time. But a new UZH study conducted with Swiss Armed Forces personnel shows that ...

How cranberries could improve memory and ward off dementia

A new study published highlights the neuroprotective potential of cranberries

23-May-2022 - Adding cranberries to your diet could help improve memory and brain function, and lower ‘bad’ cholesterol – according to new research from the University of East Anglia (UK). The research team studied the benefits of consuming the equivalent of a cup of cranberries a day among 50 to ...

Drinker’s sex plus brewing method may be key to coffee’s link to raised cholesterol

Widest gender difference seen for espresso

12-May-2022 - The sex of the drinker as well as the brewing method may be key to coffee’s link with raised cholesterol, a known risk factor for heart disease, suggests research published in the open access journal Open Heart. Drinking espresso was associated with the widest gender difference in cholesterol ...

Five childhood risk factors predict heart attacks and strokes in adulthood

This study confirms that prevention should begin in childhood

11-Apr-2022 - Five childhood risk factors that predict stroke and heart attacks in adulthood have been identified after being tracked for up to half a century in the world’s largest international prospective cardiovascular disease study. The study, conducted by the International Childhood Cardiovascular ...

Characterized drugs show unexpected effects

Known and yet unexpected: many active substances influence the cholesterol homeostasis and thereby possibly a SARS-CoV-2 infection

26-Jul-2021 - Every innovative drug starts with the search for an active substance targeting key players in disease-related processes. However, there is no perfect drug that affects the one target in the body: no effect without side effects, as also described in most medicine information leaflets. A group of ...

Cholesterol Levels Sustainably Lowered Using Base Editing

Potential therapy for patients with inherited metabolic liver diseases

21-May-2021 - Base editing is a novel gene editing approach that can precisely change individual building blocks in a DNA sequence. By installing such a point mutation in a specific gene, an international research team led by the University of Zurich has succeeded in sustainably lowering high LDL cholesterol ...

Plan B for Cholesterol Transport

Research team proves the existence of a previously unknown alternative cholesterol transport mechanism inside cells

16-Aug-2019 - Cholesterol is a vital cell building block in humans and animals, and an integral part of the so-called cell membrane. This boundary layer separates the interior of the cell from the neighbouring cells and the surrounding environment. By means of certain proteins, it ensures that various chemical ...

How “good cholesterol” gets to do even more good work

13-Aug-2019 - In order for a tumour to grow, it needs cholesterol to build new cell walls. At the same time, the so-called “good” cholesterol or high-density lipoprotein (HDL) is regarded as a protective factor against cancer. Schrödinger fellow Raimund Bauer investigated the effect of HDL on tumours more ...