Design organoids with light

Organoids help researchers understand biological processes in health and disease

01-Nov-2023 - They look like thunderclouds in pinhead format: organoids. The three-dimensional cell cultures play an important role in medical and clinical research because they reproduce tissue structures and organ functions in the Petri dish. Scientists can use them to understand how diseases arise, organs ...

Creating 3D objects with sound

Scientists introduce a new technology to assemble matter in 3D using sound waves for 3D printing

14-Feb-2023 - Scientists from the Micro, Nano and Molecular Systems Lab at the Max Planck Institute for Medical Research and the Institute for Molecular Systems Engineering and Advanced Materials at Heidelberg University have created a new technology to assemble matter in 3D. Their concept uses multiple ...

Model system provides insight into the growth of pancreatic tumors

Researchers develop innovative organoid model to study pancreatic cancer

07-Oct-2022 - Researchers at the Technical University of Munich (TUM) have developed a novel model system that can be used to precisely track the growth steps and three-dimensional arrangement of pancreatic cancer cells. It also provides the basis for testing and developing therapeutic approaches. Pancreatic ...

Cell-culture breakthrough: Advanced “mini brains” in the dish

Organoids that mimic human brain cortex in development and disease

27-Jun-2022 - “Outer Radial Glia” (oRG) cells are nervous system stem cells that are instrumental for the development of the human cortex and have been challenging to produce in the lab. Now, a team of Max Planck researchers from Berlin succeeded in generating brain organoids that are enriched with these stem ...

Immune Cells Forget (Cell) Culture Shock

The results pave the way to new macrophage-based cell therapies

28-Feb-2022 - A recent study shows that certain immune cells can restore their normal functions when introduced back into the body, even after being multiplied in the laboratory to large numbers – the results pave the way to new cell therapies. Macrophages are immune cells crucial for immune response, tissue ...

New approach to Alzheimer's therapy - researchers identify key target molecule

03-Aug-2010 - Researchers from the German Centre for Neurodegenerative Diseases (DZNE) and the Ludwig-Maximilians-Universität (LMU) in Munich have shown that the ADAM10 protein can inhibit the formation of beta-amyloid, which is responsible for Alzheimer’s disease. ADAM10 acts like a pair of molecular scissors ...