Successfully reducing animal testing: The 3Rs principle in fish research

Investigation of cell cultures provides insights into climate change

23-Jun-2023 - According to animal experimentation statistics, fish are the second most commonly used group of animals in research after mice. They play an important role in aquaculture and also serve as model animals in various research areas. "Applying the 3Rs principle means reducing, refining and replacing ...

First synthetic tissue model developed in which blood vessels can grow

02-Aug-2021 - A research team headed by biomedical engineer Dr Britta Trappmann from the Max Planck Institute for Molecular Biomedicine in Münster, Germany, has developed a cell culture system in which, for the first time, a functional blood vessel system is able to grow within a framework made of synthetic ...

Do chemicals make you fat?

The EU research project EDCMET is investigating the effect of endocrine disruptors on metabolism

28-Jan-2019 - January 2019 saw the launch of the EU research project EDCMET, in which scientists from the German Federal Institute for Risk Assessment (BfR) are also involved. EDCMET stands for "Metabolic effects of Endocrine Disrupting Chemicals: novel testing METhods and adverse outcome path-ways" and is ...

Drug discovery for Parkinson’s disease: Researchers Grow Neurons in 3D

02-Jul-2015 - The progressive loss of neurons in the brain of Parkinson’s patients is slow yet inexorable. So far, there are no drugs that can halt this insidious process. Researchers at the Luxembourg Centre for Systems Biomedicine (LCSB) of the University of Luxembourg have now managed to grow the types of ...

New screening tool could speed development of ovarian cancer drugs

12-Feb-2015 - University of Chicago Medicine researchers have built a model system that uses multiple cell types from patients to rapidly test compounds that could block the early steps in ovarian cancer metastasis. Their three-dimensional cell-culture system, adapted for high-throughput screening, has enabled ...

Pancreatic stem cells isolated from mice

18-Sep-2013 - Scientists have succeeded in growing stem cells that have the ability to develop into two different types of cells that make up a healthy pancreas. The research team led by Dr. Hans Clevers of the Hubrecht Institute, The Netherlands, have isolated and grown stem cells from the pancreases of mice ...